Atlas of Genetics and Cytogenetics in Oncology and Haematology

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GALE (UDP-galactose-4-epimerase)

Identity

Alias_namesgalactose-4-epimerase, UDP-
Alias_symbol (synonym)SDR1E1
Other alias
HGNC (Hugo) GALE
LocusID (NCBI) 2582
Atlas_Id 40683
Location 1p36.11  [Link to chromosome band 1p36]
Location_base_pair Starts at 23795599 and ends at 23799570 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GALE (1p36.11) / MPHOSPH8 (13q12.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GALE   4116
Cards
Entrez_Gene (NCBI)GALE  2582  UDP-galactose-4-epimerase
AliasesSDR1E1
GeneCards (Weizmann)GALE
Ensembl hg19 (Hinxton)ENSG00000117308 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000117308 [Gene_View]  ENSG00000117308 [Sequence]  chr1:23795599-23799570 [Contig_View]  GALE [Vega]
ICGC DataPortalENSG00000117308
TCGA cBioPortalGALE
AceView (NCBI)GALE
Genatlas (Paris)GALE
WikiGenes2582
SOURCE (Princeton)GALE
Genetics Home Reference (NIH)GALE
Genomic and cartography
GoldenPath hg38 (UCSC)GALE  -     chr1:23795599-23799570 -  1p36.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GALE  -     1p36.11   [Description]    (hg19-Feb_2009)
GoldenPathGALE - 1p36.11 [CytoView hg19]  GALE - 1p36.11 [CytoView hg38]
ImmunoBaseENSG00000117308
Mapping of homologs : NCBIGALE [Mapview hg19]  GALE [Mapview hg38]
OMIM230350   606953   
Gene and transcription
Genbank (Entrez)AK057302 AK096127 AK307354 AK314397 AL530475
RefSeq transcript (Entrez)NM_000403 NM_001008216 NM_001127621
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GALE
Cluster EST : UnigeneHs.632380 [ NCBI ]
CGAP (NCI)Hs.632380
Alternative Splicing GalleryENSG00000117308
Gene ExpressionGALE [ NCBI-GEO ]   GALE [ EBI - ARRAY_EXPRESS ]   GALE [ SEEK ]   GALE [ MEM ]
Gene Expression Viewer (FireBrowse)GALE [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2582
GTEX Portal (Tissue expression)GALE
Human Protein AtlasENSG00000117308-GALE [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14376   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14376  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14376
Splice isoforms : SwissVarQ14376
Catalytic activity : Enzyme5.1.3.2 [ Enzyme-Expasy ]   5.1.3.25.1.3.2 [ IntEnz-EBI ]   5.1.3.2 [ BRENDA ]   5.1.3.2 [ KEGG ]   
PhosPhoSitePlusQ14376
Domains : Interpro (EBI)NAD(P)-bd_dom    NAD(P)-bd_dom_sf    Nuc_sugar_epim    UDP_G4E   
Domain families : Pfam (Sanger)GDP_Man_Dehyd (PF16363)   
Domain families : Pfam (NCBI)pfam16363   
Conserved Domain (NCBI)GALE
DMDM Disease mutations2582
Blocks (Seattle)GALE
PDB (RSDB)1EK5    1EK6    1HZJ    1I3K    1I3L    1I3M    1I3N   
PDB Europe1EK5    1EK6    1HZJ    1I3K    1I3L    1I3M    1I3N   
PDB (PDBSum)1EK5    1EK6    1HZJ    1I3K    1I3L    1I3M    1I3N   
PDB (IMB)1EK5    1EK6    1HZJ    1I3K    1I3L    1I3M    1I3N   
Structural Biology KnowledgeBase1EK5    1EK6    1HZJ    1I3K    1I3L    1I3M    1I3N   
SCOP (Structural Classification of Proteins)1EK5    1EK6    1HZJ    1I3K    1I3L    1I3M    1I3N   
CATH (Classification of proteins structures)1EK5    1EK6    1HZJ    1I3K    1I3L    1I3M    1I3N   
SuperfamilyQ14376
Human Protein Atlas [tissue]ENSG00000117308-GALE [tissue]
Peptide AtlasQ14376
HPRD06092
IPIIPI00553131   IPI00030229   IPI00644364   IPI00644339   IPI00641123   IPI00515014   
Protein Interaction databases
DIP (DOE-UCLA)Q14376
IntAct (EBI)Q14376
FunCoupENSG00000117308
BioGRIDGALE
STRING (EMBL)GALE
ZODIACGALE
Ontologies - Pathways
QuickGOQ14376
Ontology : AmiGOUDP-N-acetylglucosamine 4-epimerase activity  UDP-glucose 4-epimerase activity  UDP-glucose 4-epimerase activity  cytosol  cytosol  galactose catabolic process  galactose catabolic process  galactose catabolic process  galactose catabolic process via UDP-galactose  identical protein binding  protein homodimerization activity  
Ontology : EGO-EBIUDP-N-acetylglucosamine 4-epimerase activity  UDP-glucose 4-epimerase activity  UDP-glucose 4-epimerase activity  cytosol  cytosol  galactose catabolic process  galactose catabolic process  galactose catabolic process  galactose catabolic process via UDP-galactose  identical protein binding  protein homodimerization activity  
Pathways : KEGGGalactose metabolism    Amino sugar and nucleotide sugar metabolism   
NDEx NetworkGALE
Atlas of Cancer Signalling NetworkGALE
Wikipedia pathwaysGALE
Orthology - Evolution
OrthoDB2582
GeneTree (enSembl)ENSG00000117308
Phylogenetic Trees/Animal Genes : TreeFamGALE
HOGENOMQ14376
Homologs : HomoloGeneGALE
Homology/Alignments : Family Browser (UCSC)GALE
Gene fusions - Rearrangements
Fusion : QuiverGALE
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGALE [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GALE
dbVarGALE
ClinVarGALE
1000_GenomesGALE 
Exome Variant ServerGALE
ExAC (Exome Aggregation Consortium)ENSG00000117308
GNOMAD BrowserENSG00000117308
Varsome BrowserGALE
Genetic variants : HAPMAP2582
Genomic Variants (DGV)GALE [DGVbeta]
DECIPHERGALE [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGALE 
Mutations
ICGC Data PortalGALE 
TCGA Data PortalGALE 
Broad Tumor PortalGALE
OASIS PortalGALE [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGALE  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGALE
Mutations and Diseases : HGMDGALE
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GALE
DgiDB (Drug Gene Interaction Database)GALE
DoCM (Curated mutations)GALE (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GALE (select a term)
intoGenGALE
Cancer3DGALE(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM230350    606953   
Orphanet21319    21318   
DisGeNETGALE
MedgenGALE
Genetic Testing Registry GALE
NextProtQ14376 [Medical]
TSGene2582
GENETestsGALE
Target ValidationGALE
Huge Navigator GALE [HugePedia]
snp3D : Map Gene to Disease2582
BioCentury BCIQGALE
ClinGenGALE
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2582
Chemical/Pharm GKB GenePA28531
Clinical trialGALE
Miscellaneous
canSAR (ICR)GALE (select the gene name)
DataMed IndexGALE
Probes
Litterature
PubMed45 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGALE
EVEXGALE
GoPubMedGALE
iHOPGALE
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 17:44:22 CET 2019
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