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GALR2 (galanin receptor 2)

Identity

Other namesGAL2-R
GALNR2
GALR-2
HGNC (Hugo) GALR2
LocusID (NCBI) 8811
Atlas_Id 45716
Location 17q25.1
Location_base_pair Starts at 74070882 and ends at 74073622 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GALR2   4133
Cards
Entrez_Gene (NCBI)GALR2  8811  galanin receptor 2
GeneCards (Weizmann)GALR2
Ensembl hg19 (Hinxton)ENSG00000182687 [Gene_View]  chr17:74070882-74073622 [Contig_View]  GALR2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000182687 [Gene_View]  chr17:74070882-74073622 [Contig_View]  GALR2 [Vega]
ICGC DataPortalENSG00000182687
TCGA cBioPortalGALR2
AceView (NCBI)GALR2
Genatlas (Paris)GALR2
WikiGenes8811
SOURCE (Princeton)GALR2
Genomic and cartography
GoldenPath hg19 (UCSC)GALR2  -     chr17:74070882-74073622 +  17q25.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GALR2  -     17q25.1   [Description]    (hg38-Dec_2013)
EnsemblGALR2 - 17q25.1 [CytoView hg19]  GALR2 - 17q25.1 [CytoView hg38]
Mapping of homologs : NCBIGALR2 [Mapview hg19]  GALR2 [Mapview hg38]
OMIM603691   
Gene and transcription
Genbank (Entrez)AF040630 AF080586 BC069130 BC074914 BC074915
RefSeq transcript (Entrez)NM_003857
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)GALR2
Cluster EST : UnigeneHs.666366 [ NCBI ]
CGAP (NCI)Hs.666366
Alternative Splicing : Fast-db (Paris)GSHG0012831
Alternative Splicing GalleryENSG00000182687
Gene ExpressionGALR2 [ NCBI-GEO ]   GALR2 [ EBI - ARRAY_EXPRESS ]   GALR2 [ SEEK ]   GALR2 [ MEM ]
Gene Expression Viewer (FireBrowse)GALR2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
BioGPS (Tissue expression)8811
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43603 (Uniprot)
NextProtO43603  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43603
Splice isoforms : SwissVarO43603 (Swissvar)
PhosPhoSitePlusO43603
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GAL2_rcpt    Galanin_rcpt    GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
DMDM Disease mutations8811
Blocks (Seattle)GALR2
SuperfamilyO43603
Human Protein AtlasENSG00000182687
Peptide AtlasO43603
HPRD04735
IPIIPI00013353   
Protein Interaction databases
DIP (DOE-UCLA)O43603
IntAct (EBI)O43603
FunCoupENSG00000182687
BioGRIDGALR2
STRING (EMBL)GALR2
ZODIACGALR2
Ontologies - Pathways
QuickGOO43603
Ontology : AmiGOgalanin receptor activity  protein binding  cytosol  plasma membrane  integral component of plasma membrane  muscle contraction  cell surface receptor signaling pathway  adenylate cyclase-modulating G-protein coupled receptor signaling pathway  adenylate cyclase-activating G-protein coupled receptor signaling pathway  negative regulation of adenylate cyclase activity  phospholipase C-activating G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  neuropeptide signaling pathway  synaptic transmission  multicellular organism development  digestion  learning or memory  feeding behavior  integral component of membrane  peptide hormone binding  neuron projection development  neuropeptide binding  inositol phosphate metabolic process  positive regulation of transcription from RNA polymerase II promoter  phosphatidylinositol metabolic process  positive regulation of large conductance calcium-activated potassium channel activity  
Ontology : EGO-EBIgalanin receptor activity  protein binding  cytosol  plasma membrane  integral component of plasma membrane  muscle contraction  cell surface receptor signaling pathway  adenylate cyclase-modulating G-protein coupled receptor signaling pathway  adenylate cyclase-activating G-protein coupled receptor signaling pathway  negative regulation of adenylate cyclase activity  phospholipase C-activating G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  neuropeptide signaling pathway  synaptic transmission  multicellular organism development  digestion  learning or memory  feeding behavior  integral component of membrane  peptide hormone binding  neuron projection development  neuropeptide binding  inositol phosphate metabolic process  positive regulation of transcription from RNA polymerase II promoter  phosphatidylinositol metabolic process  positive regulation of large conductance calcium-activated potassium channel activity  
Pathways : KEGGNeuroactive ligand-receptor interaction   
NDEx Network
Atlas of Cancer Signalling NetworkGALR2
Wikipedia pathwaysGALR2
Orthology - Evolution
OrthoDB8811
GeneTree (enSembl)ENSG00000182687
Phylogenetic Trees/Animal Genes : TreeFamGALR2
Homologs : HomoloGeneGALR2
Homology/Alignments : Family Browser (UCSC)GALR2
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerGALR2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GALR2
dbVarGALR2
ClinVarGALR2
1000_GenomesGALR2 
Exome Variant ServerGALR2
ExAC (Exome Aggregation Consortium)GALR2 (select the gene name)
SNP (GeneSNP Utah)GALR2
SNP : HGBaseGALR2
Genetic variants : HAPMAPGALR2
Genomic Variants (DGV)GALR2 [DGVbeta]
Mutations
ICGC Data PortalGALR2 
TCGA Data PortalGALR2 
Broad Tumor PortalGALR2
OASIS PortalGALR2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGALR2 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GALR2
DgiDB (Drug Gene Interaction Database)GALR2
DoCM (Curated mutations)GALR2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GALR2 (select a term)
intoGenGALR2
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)17:74070882-74073622
CONAN: Copy Number AnalysisGALR2 
Mutations and Diseases : HGMDGALR2
OMIM603691   
MedgenGALR2
Genetic Testing Registry GALR2
NextProtO43603 [Medical]
TSGene8811
GENETestsGALR2
Huge Navigator GALR2 [HugePedia]  GALR2 [HugeCancerGEM]
snp3D : Map Gene to Disease8811
BioCentury BCIQGALR2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8811
Chemical/Pharm GKB GenePA28546
Clinical trialGALR2
Miscellaneous
canSAR (ICR)GALR2 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGALR2
GoPubMedGALR2
iHOPGALR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Apr 16 17:45:46 CEST 2016

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