Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

GALR2 (galanin receptor 2)

Identity

Other namesGAL2-R
GALNR2
GALR-2
HGNC (Hugo) GALR2
LocusID (NCBI) 8811
Atlas_Id 45716
Location 17q25.1
Location_base_pair Starts at 74070882 and ends at 74073622 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GALR2   4133
Cards
Entrez_Gene (NCBI)GALR2  8811  galanin receptor 2
GeneCards (Weizmann)GALR2
Ensembl hg19 (Hinxton)ENSG00000182687 [Gene_View]  chr17:74070882-74073622 [Contig_View]  GALR2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000182687 [Gene_View]  chr17:74070882-74073622 [Contig_View]  GALR2 [Vega]
ICGC DataPortalENSG00000182687
TCGA cBioPortalGALR2
AceView (NCBI)GALR2
Genatlas (Paris)GALR2
WikiGenes8811
SOURCE (Princeton)GALR2
Genomic and cartography
GoldenPath hg19 (UCSC)GALR2  -     chr17:74070882-74073622 +  17q25.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GALR2  -     17q25.1   [Description]    (hg38-Dec_2013)
EnsemblGALR2 - 17q25.1 [CytoView hg19]  GALR2 - 17q25.1 [CytoView hg38]
Mapping of homologs : NCBIGALR2 [Mapview hg19]  GALR2 [Mapview hg38]
OMIM603691   
Gene and transcription
Genbank (Entrez)AF040630 AF080586 BC069130 BC074914 BC074915
RefSeq transcript (Entrez)NM_003857
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)GALR2
Cluster EST : UnigeneHs.666366 [ NCBI ]
CGAP (NCI)Hs.666366
Alternative Splicing : Fast-db (Paris)GSHG0012831
Alternative Splicing GalleryENSG00000182687
Gene ExpressionGALR2 [ NCBI-GEO ]     GALR2 [ SEEK ]   GALR2 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43603 (Uniprot)
NextProtO43603  [Medical]  [Publications]
With graphics : InterProO43603
Splice isoforms : SwissVarO43603 (Swissvar)
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GAL2_rcpt    Galanin_rcpt    GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Related proteins : CluSTrO43603
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
DMDM Disease mutations8811
Blocks (Seattle)O43603
Human Protein AtlasENSG00000182687
Peptide AtlasO43603
HPRD04735
IPIIPI00013353   
Protein Interaction databases
DIP (DOE-UCLA)O43603
IntAct (EBI)O43603
FunCoupENSG00000182687
BioGRIDGALR2
IntegromeDBGALR2
STRING (EMBL)GALR2
Ontologies - Pathways
QuickGOO43603
Ontology : AmiGOgalanin receptor activity  protein binding  cytosol  cytosol  plasma membrane  muscle contraction  cell surface receptor signaling pathway  adenylate cyclase-modulating G-protein coupled receptor signaling pathway  negative regulation of adenylate cyclase activity  positive regulation of cytosolic calcium ion concentration  neuropeptide signaling pathway  neuropeptide signaling pathway  neuropeptide signaling pathway  synaptic transmission  multicellular organismal development  digestion  learning or memory  feeding behavior  integral component of membrane  peptide hormone binding  neuron projection development  positive regulation of transcription from RNA polymerase II promoter  positive regulation of large conductance calcium-activated potassium channel activity  
Ontology : EGO-EBIgalanin receptor activity  protein binding  cytosol  cytosol  plasma membrane  muscle contraction  cell surface receptor signaling pathway  adenylate cyclase-modulating G-protein coupled receptor signaling pathway  negative regulation of adenylate cyclase activity  positive regulation of cytosolic calcium ion concentration  neuropeptide signaling pathway  neuropeptide signaling pathway  neuropeptide signaling pathway  synaptic transmission  multicellular organismal development  digestion  learning or memory  feeding behavior  integral component of membrane  peptide hormone binding  neuron projection development  positive regulation of transcription from RNA polymerase II promoter  positive regulation of large conductance calcium-activated potassium channel activity  
Pathways : KEGGNeuroactive ligand-receptor interaction   
Protein Interaction DatabaseGALR2
DoCM (Curated mutations)GALR2
Wikipedia pathwaysGALR2
Gene fusion - Rearrangements
Gene fusion: TCGA
Polymorphisms : SNP, variants
NCBI Variation ViewerGALR2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GALR2
dbVarGALR2
ClinVarGALR2
1000_GenomesGALR2 
Exome Variant ServerGALR2
SNP (GeneSNP Utah)GALR2
SNP : HGBaseGALR2
Genetic variants : HAPMAPGALR2
Genomic Variants (DGV)GALR2 [DGVbeta]
Mutations
ICGC Data PortalGALR2 
TCGA Data PortalGALR2 
Tumor PortalGALR2
Somatic Mutations in Cancer : COSMICGALR2 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)17:74070882-74073622
CONAN: Copy Number AnalysisGALR2 
Mutations and Diseases : HGMDGALR2
OMIM603691   
MedgenGALR2
NextProtO43603 [Medical]
GENETestsGALR2
Disease Genetic AssociationGALR2
Huge Navigator GALR2 [HugePedia]  GALR2 [HugeCancerGEM]
snp3D : Map Gene to Disease8811
DGIdb (Drug Gene Interaction db)GALR2
BioCentury BCIQGALR2
General knowledge
Homologs : HomoloGeneGALR2
Homology/Alignments : Family Browser (UCSC)GALR2
Phylogenetic Trees/Animal Genes : TreeFamGALR2
Chemical/Protein Interactions : CTD8811
Chemical/Pharm GKB GenePA28546
Clinical trialGALR2
Cancer Resource (Charite)ENSG00000182687
Other databases
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
CoreMineGALR2
GoPubMedGALR2
iHOPGALR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Jun 27 11:36:03 CEST 2015

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.