GALR3 (galanin receptor 3)

2007-02-01 Affiliation

Identity

HGNC

GALR3

LOCATION

22q13.1

LOCUSID

8484

ALIAS

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 8484
MIM: 603692
HGNC: 4134
Ensembl: ENSG00000128310

Variants:

dbSNP: 8484
ClinVar: 8484
TCGA: ENSG00000128310
COSMIC: GALR3

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000128310	ENST00000249041	O60755

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Neuroactive ligand-receptor interaction	KEGG	ko04080
Neuroactive ligand-receptor interaction	KEGG	hsa04080
Signal Transduction	REACTOME	R-HSA-162582
Signaling by GPCR	REACTOME	R-HSA-372790
GPCR ligand binding	REACTOME	R-HSA-500792
Class A/1 (Rhodopsin-like receptors)	REACTOME	R-HSA-373076
Peptide ligand-binding receptors	REACTOME	R-HSA-375276
GPCR downstream signaling	REACTOME	R-HSA-388396
G alpha (i) signalling events	REACTOME	R-HSA-418594

References

Pubmed ID	Year	Title	Citations
19086053	2009	Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.	34
20398908	2010	Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients.	32
24517231	2014	Coevolution of the spexin/galanin/kisspeptin family: Spexin activates galanin receptor type II and III.	32
24706871	2014	Brain galanin system genes interact with life stresses in depression-related phenotypes.	28
17083333	2007	Alcoholism is associated with GALR3 but not two other galanin receptor genes.	24
17083333	2007	Alcoholism is associated with GALR3 but not two other galanin receptor genes.	24
20677014	2010	An approach based on a genome-wide association study reveals candidate loci for narcolepsy.	16
27940914	2016	Alterations in the neuropeptide galanin system in major depressive disorder involve levels of transcripts, methylation, and peptide.	11
11867941	2002	Elevated expression of galanin receptors in childhood neuroblastic tumors.	5
28844939	2018	Lack of Galanin Receptor 3 Alleviates Psoriasis by Altering Vascularization, Immune Cell Infiltration, and Cytokine Expression.	5

Citation

Dessen P

GALR3 (galanin receptor 3)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46177/galr3