GAS2L1 (growth arrest specific 2 like 1)

2014-11-01  

Identity

HGNC
GAS2L1
LOCATION
22q12.2
LOCUSID
10634
ALIAS
GAR22
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10634
MIM: 602128
HGNC: 16955
Ensembl: ENSG00000185340

Variants:

dbSNP: 10634
ClinVar: 10634
TCGA: ENSG00000185340
COSMIC: GAS2L1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185340ENST00000406549Q99501
ENSG00000185340ENST00000416823C9JFI0
ENSG00000185340ENST00000428622C9JRR6
ENSG00000185340ENST00000610653Q99501
ENSG00000185340ENST00000610653A0A384P5D0
ENSG00000185340ENST00000611648A0A5E8
ENSG00000185340ENST00000616432A0A5E8
ENSG00000185340ENST00000618518A0A5E8
ENSG00000185340ENST00000621062A0A5E8

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
247069502014GAS2-like proteins mediate communication between microtubules and actin through interactions with end-binding proteins.21
125842482003Protein products of human Gas2-related genes on chromosomes 17 and 22 (hGAR17 and hGAR22) associate with both microfilaments and microtubules.20
193756452009GAR22: a novel target gene of thyroid hormone receptor causes growth inhibition in human erythroid cells.8
280176162017GAS2L1 Is a Centriole-Associated Protein Required for Centrosome Dynamics and Disjunction.8
205377212011An association study on polymorphisms in the PEA15, ENTPD4, and GAS2L1 genes and schizophrenia.4
205377212011An association study on polymorphisms in the PEA15, ENTPD4, and GAS2L1 genes and schizophrenia.4

Citation

Dessen P

GAS2L1 (growth arrest specific 2 like 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63703/gas2l1