GAS2L3 (growth arrest specific 2 like 3)

2014-11-01  

Identity

HGNC
GAS2L3
LOCATION
12q23.1
LOCUSID
283431
ALIAS
G2L3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 283431
MIM: 617224
HGNC: 27475
Ensembl: ENSG00000139354

Variants:

dbSNP: 283431
ClinVar: 283431
TCGA: ENSG00000139354
COSMIC: GAS2L3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000139354ENST00000266754Q86XJ1
ENSG00000139354ENST00000266754A0A024RBF4
ENSG00000139354ENST00000537247G3V1N3
ENSG00000139354ENST00000539410Q86XJ1
ENSG00000139354ENST00000539410A0A024RBF4
ENSG00000139354ENST00000547754Q86XJ1
ENSG00000139354ENST00000547754A0A024RBF4
ENSG00000139354ENST00000550295F8VSB7
ENSG00000139354ENST00000552854H0YIT6

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
234690162013Gas2l3, a novel constriction site-associated protein whose regulation is mediated by the APC/C Cdh1 complex.11
215618672011Characterization of G2L3 (GAS2-like 3), a new microtubule- and actin-binding protein related to spectraplakins.0
223442562012GAS2L3, a target gene of the DREAM complex, is required for proper cytokinesis and genomic stability.0
245715732014The GAR domain of GAS2L3 mediates binding to the chromosomal passenger complex and is required for localization of GAS2L3 to the constriction zone during abscission.0

Citation

Dessen P

GAS2L3 (growth arrest specific 2 like 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63706/gas2l3