GBP3 (guanylate binding protein 3)

2018-02-01  

Identity

HGNC
LOCATION
1p22.2
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 2635
MIM: 600413
HGNC: 4184
Ensembl: ENSG00000117226

Variants:

dbSNP: 2635
ClinVar: 2635
TCGA: ENSG00000117226
COSMIC: GBP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000117226ENST00000235878F6SPX6
ENSG00000117226ENST00000370481Q9H0R5
ENSG00000117226ENST00000445969Q5T8M0
ENSG00000117226ENST00000461384H3BNS1
ENSG00000117226ENST00000489444F6X827
ENSG00000117226ENST00000493594H3BRX6
ENSG00000117226ENST00000564665H3BPH2
ENSG00000117226ENST00000568006H3BP53

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
NOD-like receptor signaling pathwayKEGGko04621
NOD-like receptor signaling pathwayKEGGhsa04621
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Interferon SignalingREACTOMER-HSA-913531
Interferon gamma signalingREACTOMER-HSA-877300

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
221063662012A new splice variant of the human guanylate-binding protein 3 mediates anti-influenza activity through inhibition of viral transcription and replication.34
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
291283632018GBP3 promotes glioma cell proliferation via SQSTM1/p62-ERK1/2 axis.7

Citation

Dessen P

GBP3 (guanylate binding protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2018-02-01

Online version: http://atlasgeneticsoncology.org/gene/57287/gbp3