GDE1 (glycerophosphodiester phosphodiesterase 1)

2010-10-01  

Identity

HGNC
GDE1
LOCATION
16p12.3
LOCUSID
51573
ALIAS
363E6.2,MIR16
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51573
MIM: 605943
HGNC: 29644
Ensembl: ENSG00000006007

Variants:

dbSNP: 51573
ClinVar: 51573
TCGA: ENSG00000006007
COSMIC: GDE1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000006007ENST00000353258Q9NZC3
ENSG00000006007ENST00000564172H3BU22
ENSG00000006007ENST00000569773H3BNA5
ENSG00000006007ENST00000569899H3BRL5

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Phospholipid metabolismREACTOMER-HSA-1483257
PI MetabolismREACTOMER-HSA-1483255
Glycerophospholipid catabolismREACTOMER-HSA-6814848

References

Pubmed IDYearTitleCitations
340883042021Downregulation of exosomal let-7d and miR-16 in idiopathic pulmonary fibrosis.12
340883042021Downregulation of exosomal let-7d and miR-16 in idiopathic pulmonary fibrosis.12
320777472020Long Noncoding RNA DLX6-AS1 Promotes the Progression in Cervical Cancer by Targeting miR-16-5p/ARPP19 Axis.20
328626122020Solanine inhibits proliferation and promotes apoptosis of the human leukemia cells by targeting the miR-16/Bcl-2 axis.2
320777472020Long Noncoding RNA DLX6-AS1 Promotes the Progression in Cervical Cancer by Targeting miR-16-5p/ARPP19 Axis.20
328626122020Solanine inhibits proliferation and promotes apoptosis of the human leukemia cells by targeting the miR-16/Bcl-2 axis.2
294221132018Puerarin Inhibits Proliferation and Induces Apoptosis by Upregulation of miR-16 in Bladder Cancer Cell Line T24.12
296689222018Circulating and Fecal microRNAs as Biomarkers for Inflammatory Bowel Diseases.61
298031772018miR-15a/miR-16 cluster inhibits invasion of prostate cancer cells by suppressing TGF-β signaling pathway.37
294221132018Puerarin Inhibits Proliferation and Induces Apoptosis by Upregulation of miR-16 in Bladder Cancer Cell Line T24.12
296689222018Circulating and Fecal microRNAs as Biomarkers for Inflammatory Bowel Diseases.61
298031772018miR-15a/miR-16 cluster inhibits invasion of prostate cancer cells by suppressing TGF-β signaling pathway.37
287747752017miR-15a/16 inhibits TGF-beta3/VEGF signaling and increases retinal endothelial cell barrier proteins.14
290873862017TYRP1 mRNA goes fishing for miRNAs in melanoma.9
290896192017miR-16 and miR-103 impact 5-HT(4) receptor signalling and correlate with symptom profile in irritable bowel syndrome.24

Citation

Dessen P

GDE1 (glycerophosphodiester phosphodiesterase 1)

Atlas Genet Cytogenet Oncol Haematol. 2010-10-01

Online version: http://atlasgeneticsoncology.org/gene/51727/gde1