GDF10 (growth differentiation factor 10)

2004-02-01  

Identity

HGNC
LOCATION
10q11.22
LOCUSID
ALIAS
BIP,BMP-3b,BMP3B

Other Information

Locus ID:

NCBI: 2662
MIM: 601361
HGNC: 4215
Ensembl: ENSG00000266524

Variants:

dbSNP: 2662
ClinVar: 2662
TCGA: ENSG00000266524
COSMIC: GDF10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000266524ENST00000580279P55107

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
382455332024Reduced plasma GDF10 levels are positively associated with cholesterol impairment and childhood obesity.0
382455332024Reduced plasma GDF10 levels are positively associated with cholesterol impairment and childhood obesity.0
336572652022Cancer-associated fibroblasts promote tumor progression by lncRNA-mediated RUNX2/GDF10 signaling in oral squamous cell carcinoma.14
349223362022GDF10 inhibits cell proliferation and epithelial-mesenchymal transition in nasopharyngeal carcinoma by the transforming growth factor-β/Smad and NF-κB pathways.4
351637192022Single-Cell Analysis Uncovers Osteoblast Factor Growth Differentiation Factor 10 as Mediator of Vascular Smooth Muscle Cell Phenotypic Modulation Associated with Plaque Rupture in Human Carotid Artery Disease.11
336572652022Cancer-associated fibroblasts promote tumor progression by lncRNA-mediated RUNX2/GDF10 signaling in oral squamous cell carcinoma.14
349223362022GDF10 inhibits cell proliferation and epithelial-mesenchymal transition in nasopharyngeal carcinoma by the transforming growth factor-β/Smad and NF-κB pathways.4
351637192022Single-Cell Analysis Uncovers Osteoblast Factor Growth Differentiation Factor 10 as Mediator of Vascular Smooth Muscle Cell Phenotypic Modulation Associated with Plaque Rupture in Human Carotid Artery Disease.11
331708062021Mesenchymal Bmp3b expression maintains skeletal muscle integrity and decreases in age-related sarcopenia.48
331708062021Mesenchymal Bmp3b expression maintains skeletal muscle integrity and decreases in age-related sarcopenia.48
311475292019GDF10 inhibits proliferation and epithelial-mesenchymal transition in triple-negative breast cancer via upregulation of Smad7.25
311475292019GDF10 inhibits proliferation and epithelial-mesenchymal transition in triple-negative breast cancer via upregulation of Smad7.25
257282122016Loss of GDF10/BMP3b as a prognostic marker collaborates with TGFBR3 to enhance chemotherapy resistance and epithelial-mesenchymal transition in oral squamous cell carcinoma.18
257282122016Loss of GDF10/BMP3b as a prognostic marker collaborates with TGFBR3 to enhance chemotherapy resistance and epithelial-mesenchymal transition in oral squamous cell carcinoma.18
265022612015GDF10 is a signal for axonal sprouting and functional recovery after stroke.78

Citation

Dessen P

GDF10 (growth differentiation factor 10)

Atlas Genet Cytogenet Oncol Haematol. 2004-02-01

Online version: http://atlasgeneticsoncology.org/gene/40700/gdf10