GDI2 (GDP dissociation inhibitor 2)

2007-02-01  

Identity

HGNC
LOCATION
10p15.1
LOCUSID
ALIAS
HEL-S-46e,RABGDIB
FUSION GENES

Other Information

Locus ID:

NCBI: 2665
MIM: 600767
HGNC: 4227
Ensembl: ENSG00000057608

Variants:

dbSNP: 2665
ClinVar: 2665
TCGA: ENSG00000057608
COSMIC: GDI2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000057608ENST00000380127Q5SX90
ENSG00000057608ENST00000380181P50395
ENSG00000057608ENST00000380191P50395
ENSG00000057608ENST00000380191Q6IAT1
ENSG00000057608ENST00000418688Q5SX86
ENSG00000057608ENST00000447751Q5SX91
ENSG00000057608ENST00000456041Q5SX87
ENSG00000057608ENST00000608581V9GYF8
ENSG00000057608ENST00000609712V9GYJ7

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
Rho GTPase cycleREACTOMER-HSA-194840
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Neutrophil degranulationREACTOMER-HSA-6798695
RAB GEFs exchange GTP for GDP on RABsREACTOMER-HSA-8876198

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.69
175072992007Serum proteomic-based analysis of pancreatic carcinoma for the identification of potential cancer biomarkers.26
117717572001Reduction of nucleoside diphosphate kinase B, Rab GDP-dissociation inhibitor beta and histidine triad nucleotide-binding protein in fetal Down syndrome brain.5

Citation

Dessen P

GDI2 (GDP dissociation inhibitor 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43809/gdi2