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GET3 (guided entry of tail-anchored proteins factor 3, ATPase)

Identity

Alias_namesASNA1
arsA (bacterial) arsenite transporter, ATP-binding, homolog 1
Alias_symbol (synonym)ARSA-I
TRC40
Other aliasARSA1
ASNA-I
HGNC (Hugo) GET3
LocusID (NCBI) 439
Atlas_Id 57981
Location 19p13.13  [Link to chromosome band 19p13]
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)GET3   752
Cards
Entrez_Gene (NCBI)GET3  439  guided entry of tail-anchored proteins factor 3, ATPase
AliasesARSA-I; ARSA1; ASNA-I; ASNA1; 
TRC40
GeneCards (Weizmann)GET3
Ensembl hg19 (Hinxton)ENSG00000198356 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198356 [Gene_View]  ENSG00000198356 [Sequence]  - [Contig_View]  GET3 [Vega]
ICGC DataPortalENSG00000198356
TCGA cBioPortalGET3
AceView (NCBI)GET3
Genatlas (Paris)GET3
WikiGenes439
SOURCE (Princeton)GET3
Genetics Home Reference (NIH)GET3
Genomic and cartography
GoldenPath hg38 (UCSC)GET3  -  
GoldenPath hg19 (UCSC)GET3  -  
GoldenPathGET3 - [CytoView hg19]  GET3 - [CytoView hg38]
ImmunoBaseENSG00000198356
Mapping of homologs : NCBIGET3 [Mapview hg19]  GET3 [Mapview hg38]
OMIM601913   
Gene and transcription
Genbank (Entrez)AF047469 AK223363 AK291855 AK293588 BC002651
RefSeq transcript (Entrez)NM_001371488 NM_001371489 NM_004317
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GET3
Cluster EST : UnigeneHs.465985 [ NCBI ]
CGAP (NCI)Hs.465985
Alternative Splicing GalleryENSG00000198356
Gene ExpressionGET3 [ NCBI-GEO ]   GET3 [ EBI - ARRAY_EXPRESS ]   GET3 [ SEEK ]   GET3 [ MEM ]
Gene Expression Viewer (FireBrowse)GET3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)439
GTEX Portal (Tissue expression)GET3
Human Protein AtlasENSG00000198356-GET3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43681   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43681  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43681
Splice isoforms : SwissVarO43681
Catalytic activity : Enzyme3.6.3.16 [ Enzyme-Expasy ]   3.6.3.163.6.3.16 [ IntEnz-EBI ]   3.6.3.16 [ BRENDA ]   3.6.3.16 [ KEGG ]   
PhosPhoSitePlusO43681
Domains : Interpro (EBI)Anion-transp_ATPase-like_dom    ATPase_ArsA/GET3    ATPase_ArsA/GET3_euk    P-loop_NTPase   
Domain families : Pfam (Sanger)ArsA_ATPase (PF02374)   
Domain families : Pfam (NCBI)pfam02374   
Conserved Domain (NCBI)GET3
DMDM Disease mutations439
Blocks (Seattle)GET3
SuperfamilyO43681
Human Protein Atlas [tissue]ENSG00000198356-GET3 [tissue]
Peptide AtlasO43681
IPIIPI00013466   IPI00910220   
Protein Interaction databases
DIP (DOE-UCLA)O43681
IntAct (EBI)O43681
FunCoupENSG00000198356
BioGRIDGET3
STRING (EMBL)GET3
ZODIACGET3
Ontologies - Pathways
QuickGOO43681
Ontology : AmiGOprotein binding  ATP binding  nucleus  nucleolus  cytoplasm  endoplasmic reticulum membrane  posttranslational protein targeting to endoplasmic reticulum membrane  arsenite transmembrane transporter activity  arsenite transport  ATPase activity  IRE1-mediated unfolded protein response  GET complex  metal ion binding  extracellular exosome  tail-anchored membrane protein insertion into ER membrane  tail-anchored membrane protein insertion into ER membrane  
Ontology : EGO-EBIprotein binding  ATP binding  nucleus  nucleolus  cytoplasm  endoplasmic reticulum membrane  posttranslational protein targeting to endoplasmic reticulum membrane  arsenite transmembrane transporter activity  arsenite transport  ATPase activity  IRE1-mediated unfolded protein response  GET complex  metal ion binding  extracellular exosome  tail-anchored membrane protein insertion into ER membrane  tail-anchored membrane protein insertion into ER membrane  
NDEx NetworkGET3
Atlas of Cancer Signalling NetworkGET3
Wikipedia pathwaysGET3
Orthology - Evolution
OrthoDB439
GeneTree (enSembl)ENSG00000198356
Phylogenetic Trees/Animal Genes : TreeFamGET3
HOGENOMO43681
Homologs : HomoloGeneGET3
Homology/Alignments : Family Browser (UCSC)GET3
Gene fusions - Rearrangements
Fusion : QuiverGET3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGET3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GET3
dbVarGET3
ClinVarGET3
1000_GenomesGET3 
Exome Variant ServerGET3
ExAC (Exome Aggregation Consortium)ENSG00000198356
GNOMAD BrowserENSG00000198356
Varsome BrowserGET3
Genetic variants : HAPMAP439
Genomic Variants (DGV)GET3 [DGVbeta]
DECIPHERGET3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGET3 
Mutations
ICGC Data PortalGET3 
TCGA Data PortalGET3 
Broad Tumor PortalGET3
OASIS PortalGET3 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDGET3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GET3
DgiDB (Drug Gene Interaction Database)GET3
DoCM (Curated mutations)GET3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GET3 (select a term)
intoGenGET3
Cancer3DGET3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601913   
Orphanet
DisGeNETGET3
MedgenGET3
Genetic Testing Registry GET3
NextProtO43681 [Medical]
TSGene439
GENETestsGET3
Target ValidationGET3
Huge Navigator GET3 [HugePedia]
snp3D : Map Gene to Disease439
BioCentury BCIQGET3
ClinGenGET3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD439
Chemical/Pharm GKB GenePA25051
Clinical trialGET3
Miscellaneous
canSAR (ICR)GET3 (select the gene name)
DataMed IndexGET3
Probes
Litterature
PubMed58 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGET3
EVEXGET3
GoPubMedGET3
iHOPGET3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 17:44:44 CET 2019

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