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GGTLC3 (gamma-glutamyltransferase light chain family member 3)

Identity

Other aliasGGT
HGNC (Hugo) GGTLC3
LocusID (NCBI) 728226
Atlas_Id 80426
Location 22q11.21  [Link to chromosome band 22q11]
Location_base_pair Starts at 18516344 and ends at 18518161 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)GGTLC3   33426
Cards
Entrez_Gene (NCBI)GGTLC3  728226  gamma-glutamyltransferase light chain family member 3
AliasesGGT
GeneCards (Weizmann)GGTLC3
Ensembl hg19 (Hinxton)ENSG00000274252 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000274252 [Gene_View]  ENSG00000274252 [Sequence]  chr22:18516344-18518161 [Contig_View]  GGTLC3 [Vega]
ICGC DataPortalENSG00000274252
TCGA cBioPortalGGTLC3
AceView (NCBI)GGTLC3
Genatlas (Paris)GGTLC3
WikiGenes728226
SOURCE (Princeton)GGTLC3
Genetics Home Reference (NIH)GGTLC3
Genomic and cartography
GoldenPath hg38 (UCSC)GGTLC3  -     chr22:18516344-18518161 -  22q11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GGTLC3  -     22q11.21   [Description]    (hg19-Feb_2009)
GoldenPathGGTLC3 - 22q11.21 [CytoView hg19]  GGTLC3 - 22q11.21 [CytoView hg38]
ImmunoBaseENSG00000274252
Mapping of homologs : NCBIGGTLC3 [Mapview hg19]  GGTLC3 [Mapview hg38]
OMIM612340   
Gene and transcription
Genbank (Entrez)-
RefSeq transcript (Entrez)NM_001355479
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GGTLC3
Alternative Splicing GalleryENSG00000274252
Gene ExpressionGGTLC3 [ NCBI-GEO ]   GGTLC3 [ EBI - ARRAY_EXPRESS ]   GGTLC3 [ SEEK ]   GGTLC3 [ MEM ]
Gene Expression Viewer (FireBrowse)GGTLC3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)728226
GTEX Portal (Tissue expression)GGTLC3
Human Protein AtlasENSG00000274252-GGTLC3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtB5MD39   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtB5MD39  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProB5MD39
Splice isoforms : SwissVarB5MD39
PhosPhoSitePlusB5MD39
Domaine pattern : Prosite (Expaxy)G_GLU_TRANSPEPTIDASE (PS00462)   
Domains : Interpro (EBI)GGT_peptidase    Ntn_hydrolases_N   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)GGTLC3
DMDM Disease mutations728226
Blocks (Seattle)GGTLC3
SuperfamilyB5MD39
Human Protein Atlas [tissue]ENSG00000274252-GGTLC3 [tissue]
Peptide AtlasB5MD39
IPIIPI00552338   
Protein Interaction databases
DIP (DOE-UCLA)B5MD39
IntAct (EBI)B5MD39
FunCoupENSG00000274252
BioGRIDGGTLC3
STRING (EMBL)GGTLC3
ZODIACGGTLC3
Ontologies - Pathways
QuickGOB5MD39
Ontology : AmiGOmolecular_function  proteolysis  glutathione catabolic process  biological_process  glutathione hydrolase activity  extracellular exosome  leukotriene D4 biosynthetic process  
Ontology : EGO-EBImolecular_function  proteolysis  glutathione catabolic process  biological_process  glutathione hydrolase activity  extracellular exosome  leukotriene D4 biosynthetic process  
NDEx NetworkGGTLC3
Atlas of Cancer Signalling NetworkGGTLC3
Wikipedia pathwaysGGTLC3
Orthology - Evolution
OrthoDB728226
GeneTree (enSembl)ENSG00000274252
Phylogenetic Trees/Animal Genes : TreeFamGGTLC3
HOGENOMB5MD39
Homologs : HomoloGeneGGTLC3
Homology/Alignments : Family Browser (UCSC)GGTLC3
Gene fusions - Rearrangements
Fusion : QuiverGGTLC3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGGTLC3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GGTLC3
dbVarGGTLC3
ClinVarGGTLC3
1000_GenomesGGTLC3 
Exome Variant ServerGGTLC3
ExAC (Exome Aggregation Consortium)ENSG00000274252
GNOMAD BrowserENSG00000274252
Varsome BrowserGGTLC3
Genetic variants : HAPMAP728226
Genomic Variants (DGV)GGTLC3 [DGVbeta]
DECIPHERGGTLC3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGGTLC3 
Mutations
ICGC Data PortalGGTLC3 
TCGA Data PortalGGTLC3 
Broad Tumor PortalGGTLC3
OASIS PortalGGTLC3 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDGGTLC3
BioMutasearch GGTLC3
DgiDB (Drug Gene Interaction Database)GGTLC3
DoCM (Curated mutations)GGTLC3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GGTLC3 (select a term)
intoGenGGTLC3
Cancer3DGGTLC3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612340   
Orphanet
DisGeNETGGTLC3
MedgenGGTLC3
Genetic Testing Registry GGTLC3
NextProtB5MD39 [Medical]
TSGene728226
GENETestsGGTLC3
Target ValidationGGTLC3
Huge Navigator GGTLC3 [HugePedia]
snp3D : Map Gene to Disease728226
BioCentury BCIQGGTLC3
ClinGenGGTLC3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD728226
Chemical/Pharm GKB GenePA162389536
Clinical trialGGTLC3
Miscellaneous
canSAR (ICR)GGTLC3 (select the gene name)
DataMed IndexGGTLC3
Probes
Litterature
PubMed4 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGGTLC3
EVEXGGTLC3
GoPubMedGGTLC3
iHOPGGTLC3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Sep 3 15:29:39 CEST 2019

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