GIMAP5 (GTPase, IMAP family member 5)

2017-04-01 Affiliation

Identity

HGNC

GIMAP5

LOCATION

7q36.1

LOCUSID

55340

ALIAS

HIMAP3,IAN-5,IAN4,IAN4L1,IAN5,IMAP3,IROD

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 55340
MIM: 608086
HGNC: 18005
Ensembl: ENSG00000196329

Variants:

dbSNP: 55340
ClinVar: 55340
TCGA: ENSG00000196329
COSMIC: GIMAP5

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000196329	ENST00000358647	Q96F15
ENSG00000196329	ENST00000358647	A0A090N8P9
ENSG00000196329	ENST00000498181	Q96F15
ENSG00000196329	ENST00000498181	A0A090N8P9

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
20190135	2010	Loss of T cell and B cell quiescence precedes the onset of microbial flora-dependent wasting disease and intestinal inflammation in Gimap5-deficient mice.	34
17220214	2007	The human GIMAP5 gene has a common polyadenylation polymorphism increasing risk to systemic lupus erythematosus.	32
17220214	2007	The human GIMAP5 gene has a common polyadenylation polymorphism increasing risk to systemic lupus erythematosus.	32
20237496	2010	New genetic associations detected in a host response study to hepatitis B vaccine.	27
17641683	2007	IA-2 autoantibodies in incident type I diabetes patients are associated with a polyadenylation signal polymorphism in GIMAP5.	25
17641683	2007	IA-2 autoantibodies in incident type I diabetes patients are associated with a polyadenylation signal polymorphism in GIMAP5.	25
17369194	2007	Both Gimap5 and the diabetogenic BBDP allele of Gimap5 induce apoptosis in T cells.	15
23098229	2013	GTPase of the immune-associated nucleotide-binding protein 5 (GIMAP5) regulates calcium influx in T-lymphocytes by promoting mitochondrial calcium accumulation.	11
19762377	2009	IAN5 polymorphisms are associated with systemic lupus erythematosus.	9
19762377	2009	IAN5 polymorphisms are associated with systemic lupus erythematosus.	9

Citation

Dessen P

GIMAP5 (GTPase, IMAP family member 5)

Atlas Genet Cytogenet Oncol Haematol. 2017-04-01

Online version: http://atlasgeneticsoncology.org/gene/56756/gimap5