Atlas of Genetics and Cytogenetics in Oncology and Haematology

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GK2 (glycerol kinase 2)

Identity

Alias (NCBI)GKP2
GKTA
HGNC (Hugo) GK2
HGNC Alias symbGKTA
HGNC Previous nameGKP2
HGNC Previous nameglycerol kinase pseudogene 2
LocusID (NCBI) 2712
Atlas_Id 56873
Location 4q21.21  [Link to chromosome band 4q21]
Location_base_pair Starts at 79406361 and ends at 79408228 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GK2   4291
Cards
Entrez_Gene (NCBI)GK2  2712  glycerol kinase 2
AliasesGKP2; GKTA
GeneCards (Weizmann)GK2
Ensembl hg19 (Hinxton)ENSG00000196475 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000196475 [Gene_View]  ENSG00000196475 [Sequence]  chr4:79406361-79408228 [Contig_View]  GK2 [Vega]
ICGC DataPortalENSG00000196475
TCGA cBioPortalGK2
AceView (NCBI)GK2
Genatlas (Paris)GK2
WikiGenes2712
SOURCE (Princeton)GK2
Genetics Home Reference (NIH)GK2
Genomic and cartography
GoldenPath hg38 (UCSC)GK2  -     chr4:79406361-79408228 -  4q21.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GK2  -     4q21.21   [Description]    (hg19-Feb_2009)
GoldenPathGK2 - 4q21.21 [CytoView hg19]  GK2 - 4q21.21 [CytoView hg38]
ImmunoBaseENSG00000196475
genome Data Viewer NCBIGK2 [Mapview hg19]  
OMIM600148   
Gene and transcription
Genbank (Entrez)AK292241 AK312768 BC027598 BC029820 BC048274
RefSeq transcript (Entrez)NM_033214
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GK2
Alternative Splicing GalleryENSG00000196475
Gene ExpressionGK2 [ NCBI-GEO ]   GK2 [ EBI - ARRAY_EXPRESS ]   GK2 [ SEEK ]   GK2 [ MEM ]
Gene Expression Viewer (FireBrowse)GK2 [ Firebrowse - Broad ]
GenevisibleExpression of GK2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2712
GTEX Portal (Tissue expression)GK2
Human Protein AtlasENSG00000196475-GK2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14410   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14410  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14410
Splice isoforms : SwissVarQ14410
Catalytic activity : Enzyme2.7.1.30 [ Enzyme-Expasy ]   2.7.1.302.7.1.30 [ IntEnz-EBI ]   2.7.1.30 [ BRENDA ]   2.7.1.30 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ14410
Domaine pattern : Prosite (Expaxy)FGGY_KINASES_1 (PS00933)    FGGY_KINASES_2 (PS00445)   
Domains : Interpro (EBI)Carb_kinase_FGGY    Carb_kinase_FGGY_C    Carb_kinase_FGGY_CS    Carb_kinase_FGGY_N    GK1-3_metazoa    Glycerol_kin   
Domain families : Pfam (Sanger)FGGY_C (PF02782)    FGGY_N (PF00370)   
Domain families : Pfam (NCBI)pfam02782    pfam00370   
Conserved Domain (NCBI)GK2
DMDM Disease mutations2712
Blocks (Seattle)GK2
SuperfamilyQ14410
Human Protein Atlas [tissue]ENSG00000196475-GK2 [tissue]
Peptide AtlasQ14410
IPIIPI00419234   
Protein Interaction databases
DIP (DOE-UCLA)Q14410
IntAct (EBI)Q14410
FunCoupENSG00000196475
BioGRIDGK2
STRING (EMBL)GK2
ZODIACGK2
Ontologies - Pathways
QuickGOQ14410
Ontology : AmiGOglycerol kinase activity  glycerol kinase activity  ATP binding  mitochondrion  mitochondrial outer membrane  glycerol metabolic process  triglyceride metabolic process  phosphorylation  phosphotransferase activity, alcohol group as acceptor  glycerol catabolic process  glycerol-3-phosphate biosynthetic process  extracellular exosome  
Ontology : EGO-EBIglycerol kinase activity  glycerol kinase activity  ATP binding  mitochondrion  mitochondrial outer membrane  glycerol metabolic process  triglyceride metabolic process  phosphorylation  phosphotransferase activity, alcohol group as acceptor  glycerol catabolic process  glycerol-3-phosphate biosynthetic process  extracellular exosome  
Pathways : KEGGGlycerolipid metabolism    PPAR signaling pathway   
NDEx NetworkGK2
Atlas of Cancer Signalling NetworkGK2
Wikipedia pathwaysGK2
Orthology - Evolution
OrthoDB2712
GeneTree (enSembl)ENSG00000196475
Phylogenetic Trees/Animal Genes : TreeFamGK2
HOGENOMQ14410
Homologs : HomoloGeneGK2
Homology/Alignments : Family Browser (UCSC)GK2
Gene fusions - Rearrangements
Fusion : QuiverGK2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGK2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GK2
dbVarGK2
ClinVarGK2
1000_GenomesGK2 
Exome Variant ServerGK2
GNOMAD BrowserENSG00000196475
Varsome BrowserGK2
Genetic variants : HAPMAP2712
Genomic Variants (DGV)GK2 [DGVbeta]
DECIPHERGK2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGK2 
Mutations
ICGC Data PortalGK2 
TCGA Data PortalGK2 
Broad Tumor PortalGK2
OASIS PortalGK2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGK2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGK2
Mutations and Diseases : HGMDGK2
BioMutasearch GK2
DgiDB (Drug Gene Interaction Database)GK2
DoCM (Curated mutations)GK2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GK2 (select a term)
intoGenGK2
Cancer3DGK2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600148   
Orphanet
DisGeNETGK2
MedgenGK2
Genetic Testing Registry GK2
NextProtQ14410 [Medical]
TSGene2712
GENETestsGK2
Target ValidationGK2
Huge Navigator GK2 [HugePedia]
snp3D : Map Gene to Disease2712
BioCentury BCIQGK2
ClinGenGK2
Clinical trials, drugs, therapy
Protein Interactions : CTD2712
Pharm GKB GenePA28702
Clinical trialGK2
Miscellaneous
canSAR (ICR)GK2 (select the gene name)
HarmonizomeGK2
DataMed IndexGK2
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGK2
EVEXGK2
GoPubMedGK2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jul 16 15:14:52 CEST 2020
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