Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 200504
MIM: 618589
HGNC: 24588
Ensembl: ENSG00000183607
Variants:
dbSNP: 200504
ClinVar: 200504
TCGA: ENSG00000183607
COSMIC: GKN2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000183607 | ENST00000328895 | Q86XP6 |
| ENSG00000183607 | ENST00000481498 | E5RHQ8 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33009998 | 2021 | NK6 Homeobox 2 Regulated Gastrokin-2 Suppresses Gastric Cancer Cell Proliferation and Invasion via Akt Signaling Pathway. | 2 |
| 33009998 | 2021 | NK6 Homeobox 2 Regulated Gastrokin-2 Suppresses Gastric Cancer Cell Proliferation and Invasion via Akt Signaling Pathway. | 2 |
| 31463974 | 2020 | Multiscale network analysis reveals molecular mechanisms and key regulators of the tumor microenvironment in gastric cancer. | 10 |
| 32538140 | 2020 | Coordinate expression loss of GKN1 and GKN2 in gastric cancer via impairment of a glucocorticoid-responsive enhancer. | 5 |
| 31463974 | 2020 | Multiscale network analysis reveals molecular mechanisms and key regulators of the tumor microenvironment in gastric cancer. | 10 |
| 32538140 | 2020 | Coordinate expression loss of GKN1 and GKN2 in gastric cancer via impairment of a glucocorticoid-responsive enhancer. | 5 |
| 31382983 | 2019 | GKN2 promotes oxidative stress-induced gastric cancer cell apoptosis via the Hsc70 pathway. | 12 |
| 31382983 | 2019 | GKN2 promotes oxidative stress-induced gastric cancer cell apoptosis via the Hsc70 pathway. | 12 |
| 28150071 | 2017 | Heterodimeric interaction between GKN2 and TFF1 entails synergistic antiproliferative and pro-apoptotic effects on gastric cancer cells. | 10 |
| 28150071 | 2017 | Heterodimeric interaction between GKN2 and TFF1 entails synergistic antiproliferative and pro-apoptotic effects on gastric cancer cells. | 10 |
| 26842925 | 2016 | A possible role of GDDR in the development of Helicobacter pylori-associated gastric cancer. | 1 |
| 26974160 | 2016 | Loss of gastrokine-2 drives premalignant gastric inflammation and tumor progression. | 31 |
| 27017226 | 2016 | Gastrointestinal Factor GDDR Attenuates Epithelial-Mesenchymal Transition in Gastric Cancer via Inhibiting AKT Signal. | 0 |
| 27323966 | 2016 | Gastrokine-2 suppresses epithelial mesenchymal transition through PI3K/AKT/GSK3β signaling in gastric cancer. | 13 |
| 26842925 | 2016 | A possible role of GDDR in the development of Helicobacter pylori-associated gastric cancer. | 1 |
Citation
Dessen P
GKN2 (gastrokine 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-10-01
Online version: http://atlasgeneticsoncology.org/gene/40698/gkn2
