Identity
HGNC
LOCATION
7p14.1
LOCUSID
ALIAS
ACLS,GCPS,GLI3-190,GLI3FL,PAP-A,PAPA,PAPA1,PAPB,PHS,PPDIV
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2737
MIM: 165240
HGNC: 4319
Ensembl: ENSG00000106571
Variants:
dbSNP: 2737
ClinVar: 2737
TCGA: ENSG00000106571
COSMIC: GLI3
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36411030 | 2023 | Conclusion of diagnostic odysseys due to inversions disrupting GLI3 and FBN1. | 6 |
| 36411030 | 2023 | Conclusion of diagnostic odysseys due to inversions disrupting GLI3 and FBN1. | 6 |
| 34610962 | 2022 | GLI3 Is Stabilized by SPOP Mutations and Promotes Castration Resistance via Functional Cooperation with Androgen Receptor in Prostate Cancer. | 10 |
| 35134468 | 2022 | GLI3 and androgen receptor are mutually dependent for their malignancy-promoting activity in ovarian and breast cancer cells. | 8 |
| 35218158 | 2022 | Two nonsense GLI3 variants are associated with polydactyly and syndactyly in two families by affecting the sonic hedgehog signaling pathway. | 4 |
| 35546307 | 2022 | A novel variant of GLI3, p.Asp1514Thrfs*5, is identified in a Chinese family affected by polydactyly. | 3 |
| 35937499 | 2022 | A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling. | 1 |
| 34610962 | 2022 | GLI3 Is Stabilized by SPOP Mutations and Promotes Castration Resistance via Functional Cooperation with Androgen Receptor in Prostate Cancer. | 10 |
| 35134468 | 2022 | GLI3 and androgen receptor are mutually dependent for their malignancy-promoting activity in ovarian and breast cancer cells. | 8 |
| 35218158 | 2022 | Two nonsense GLI3 variants are associated with polydactyly and syndactyly in two families by affecting the sonic hedgehog signaling pathway. | 4 |
| 35546307 | 2022 | A novel variant of GLI3, p.Asp1514Thrfs*5, is identified in a Chinese family affected by polydactyly. | 3 |
| 35937499 | 2022 | A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling. | 1 |
| 32591344 | 2021 | Variant type and position predict two distinct limb phenotypes in patients with GLI3-mediated polydactyly syndromes. | 2 |
| 32696176 | 2021 | Compound heterozygous GLI3 variants in siblings with thyroid hemiagenesis. | 3 |
| 33058447 | 2021 | Novel GLI3 pathogenic variants in complex pre- and postaxial polysyndactyly and Greig cephalopolysyndactyly syndrome. | 3 |
Citation
Dessen P
GLI3 (GLI family zinc finger 3)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/40719/gli3
