Identity
HGNC
LOCATION
10q26.3
LOCUSID
ALIAS
GLRX4,GRX3,GRX4,PICOT,TXNL2,TXNL3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10539
MIM: 612754
HGNC: 15987
Ensembl: ENSG00000108010
Variants:
dbSNP: 10539
ClinVar: 10539
TCGA: ENSG00000108010
COSMIC: GLRX3
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34794402 | 2021 | GLRX3, a novel cancer stem cell-related secretory biomarker of pancreatic ductal adenocarcinoma. | 3 |
| 34794402 | 2021 | GLRX3, a novel cancer stem cell-related secretory biomarker of pancreatic ductal adenocarcinoma. | 3 |
| 32414791 | 2020 | Interactions of GMP with Human Glrx3 and with Saccharomyces cerevisiae Grx3 and Grx4 Converge in the Regulation of the Gcn2 Pathway. | 4 |
| 32429669 | 2020 | GLRX3 Acts as a [2Fe-2S] Cluster Chaperone in the Cytosolic Iron-Sulfur Assembly Machinery Transferring [2Fe-2S] Clusters to NUBP1. | 9 |
| 32414791 | 2020 | Interactions of GMP with Human Glrx3 and with Saccharomyces cerevisiae Grx3 and Grx4 Converge in the Regulation of the Gcn2 Pathway. | 4 |
| 32429669 | 2020 | GLRX3 Acts as a [2Fe-2S] Cluster Chaperone in the Cytosolic Iron-Sulfur Assembly Machinery Transferring [2Fe-2S] Clusters to NUBP1. | 9 |
| 30595380 | 2019 | PICOT binding to the polycomb group protein, EED, alters H3K27 methylation at the MYT1 PRC2 target gene. | 7 |
| 31176019 | 2019 | PICOT (GLRX3) is a positive regulator of stress-induced DNA-damage response. | 9 |
| 31527584 | 2019 | PICOT binding to chromatin-associated EED negatively regulates cyclin D2 expression by increasing H3K27me3 at the CCND2 gene promoter. | 5 |
| 30595380 | 2019 | PICOT binding to the polycomb group protein, EED, alters H3K27 methylation at the MYT1 PRC2 target gene. | 7 |
| 31176019 | 2019 | PICOT (GLRX3) is a positive regulator of stress-induced DNA-damage response. | 9 |
| 31527584 | 2019 | PICOT binding to chromatin-associated EED negatively regulates cyclin D2 expression by increasing H3K27me3 at the CCND2 gene promoter. | 5 |
| 29397791 | 2018 | Glutaredoxin 3 promotes migration and invasion via the Notch signalling pathway in oral squamous cell carcinoma. | 18 |
| 29397791 | 2018 | Glutaredoxin 3 promotes migration and invasion via the Notch signalling pathway in oral squamous cell carcinoma. | 18 |
| 27203742 | 2016 | Glutaredoxin 3 promotes nasopharyngeal carcinoma growth and metastasis via EGFR/Akt pathway and independent of ROS. | 9 |
Citation
Dessen P
GLRX3 (glutaredoxin 3)
Atlas Genet Cytogenet Oncol Haematol. 2008-09-01
Online version: http://atlasgeneticsoncology.org/gene/50374/glrx3
