Atlas of Genetics and Cytogenetics in Oncology and Haematology

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GLYR1 (glyoxylate reductase 1 homolog)

Identity

Alias_namesglyoxylate reductase 1 homolog (Arabidopsis)
Alias_symbol (synonym)BM045
HIBDL
NP60
N-PAC
Other aliashNDF
HGNC (Hugo) GLYR1
LocusID (NCBI) 84656
Atlas_Id 63845
Location 16p13.3  [Link to chromosome band 16p13]
Location_base_pair Starts at 4803203 and ends at 4847302 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ADCY9 (16p13.3) / GLYR1 (16p13.3)GLYR1 (16p13.3) / DCTN5 (16p12.2)GLYR1 (16p13.3) / ELAVL4 (1p33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GLYR1   24434
Cards
Entrez_Gene (NCBI)GLYR1  84656  glyoxylate reductase 1 homolog
AliasesBM045; HIBDL; N-PAC; NP60; 
hNDF
GeneCards (Weizmann)GLYR1
Ensembl hg19 (Hinxton)ENSG00000140632 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000140632 [Gene_View]  ENSG00000140632 [Sequence]  chr16:4803203-4847302 [Contig_View]  GLYR1 [Vega]
ICGC DataPortalENSG00000140632
TCGA cBioPortalGLYR1
AceView (NCBI)GLYR1
Genatlas (Paris)GLYR1
WikiGenes84656
SOURCE (Princeton)GLYR1
Genetics Home Reference (NIH)GLYR1
Genomic and cartography
GoldenPath hg38 (UCSC)GLYR1  -     chr16:4803203-4847302 -  16p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GLYR1  -     16p13.3   [Description]    (hg19-Feb_2009)
GoldenPathGLYR1 - 16p13.3 [CytoView hg19]  GLYR1 - 16p13.3 [CytoView hg38]
ImmunoBaseENSG00000140632
Mapping of homologs : NCBIGLYR1 [Mapview hg19]  GLYR1 [Mapview hg38]
OMIM610660   
Gene and transcription
Genbank (Entrez)AF217521 AF244907 AF326966 AK296842 AK307834
RefSeq transcript (Entrez)NM_001308096 NM_001324096 NM_001324097 NM_001324098 NM_032569
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GLYR1
Cluster EST : UnigeneHs.731580 [ NCBI ]
CGAP (NCI)Hs.731580
Alternative Splicing GalleryENSG00000140632
Gene ExpressionGLYR1 [ NCBI-GEO ]   GLYR1 [ EBI - ARRAY_EXPRESS ]   GLYR1 [ SEEK ]   GLYR1 [ MEM ]
Gene Expression Viewer (FireBrowse)GLYR1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84656
GTEX Portal (Tissue expression)GLYR1
Human Protein AtlasENSG00000140632-GLYR1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ49A26   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ49A26  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ49A26
Splice isoforms : SwissVarQ49A26
PhosPhoSitePlusQ49A26
Domaine pattern : Prosite (Expaxy)PWWP (PS50812)   
Domains : Interpro (EBI)6-PGluconate_DH-like_C_sf    6PGD_dom2    6PGDH_NADP-bd    NAD(P)-bd_dom_sf    NADP-bd    NP60_PWWP    PWWP_dom   
Domain families : Pfam (Sanger)NAD_binding_11 (PF14833)    NAD_binding_2 (PF03446)    PWWP (PF00855)   
Domain families : Pfam (NCBI)pfam14833    pfam03446    pfam00855   
Domain families : Smart (EMBL)PWWP (SM00293)  
Conserved Domain (NCBI)GLYR1
DMDM Disease mutations84656
Blocks (Seattle)GLYR1
PDB (RSDB)2UYY    4GUR    4GUS    4GUT    4GUU    4HSU   
PDB Europe2UYY    4GUR    4GUS    4GUT    4GUU    4HSU   
PDB (PDBSum)2UYY    4GUR    4GUS    4GUT    4GUU    4HSU   
PDB (IMB)2UYY    4GUR    4GUS    4GUT    4GUU    4HSU   
Structural Biology KnowledgeBase2UYY    4GUR    4GUS    4GUT    4GUU    4HSU   
SCOP (Structural Classification of Proteins)2UYY    4GUR    4GUS    4GUT    4GUU    4HSU   
CATH (Classification of proteins structures)2UYY    4GUR    4GUS    4GUT    4GUU    4HSU   
SuperfamilyQ49A26
Human Protein Atlas [tissue]ENSG00000140632-GLYR1 [tissue]
Peptide AtlasQ49A26
HPRD17625
IPIIPI00647648   IPI00647134   IPI00644210   IPI00910934   IPI00000155   IPI00020494   
Protein Interaction databases
DIP (DOE-UCLA)Q49A26
IntAct (EBI)Q49A26
FunCoupENSG00000140632
BioGRIDGLYR1
STRING (EMBL)GLYR1
ZODIACGLYR1
Ontologies - Pathways
QuickGOQ49A26
Ontology : AmiGOnucleosome  DNA binding  protein binding  nucleoplasm  Golgi apparatus  cytosol  oxidoreductase activity  nuclear speck  nuclear speck  methylated histone binding  methylated histone binding  histone binding  NADP binding  NAD binding  oxidation-reduction process  
Ontology : EGO-EBInucleosome  DNA binding  protein binding  nucleoplasm  Golgi apparatus  cytosol  oxidoreductase activity  nuclear speck  nuclear speck  methylated histone binding  methylated histone binding  histone binding  NADP binding  NAD binding  oxidation-reduction process  
NDEx NetworkGLYR1
Atlas of Cancer Signalling NetworkGLYR1
Wikipedia pathwaysGLYR1
Orthology - Evolution
OrthoDB84656
GeneTree (enSembl)ENSG00000140632
Phylogenetic Trees/Animal Genes : TreeFamGLYR1
HOGENOMQ49A26
Homologs : HomoloGeneGLYR1
Homology/Alignments : Family Browser (UCSC)GLYR1
Gene fusions - Rearrangements
Fusion : QuiverGLYR1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGLYR1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GLYR1
dbVarGLYR1
ClinVarGLYR1
1000_GenomesGLYR1 
Exome Variant ServerGLYR1
ExAC (Exome Aggregation Consortium)ENSG00000140632
GNOMAD BrowserENSG00000140632
Varsome BrowserGLYR1
Genetic variants : HAPMAP84656
Genomic Variants (DGV)GLYR1 [DGVbeta]
DECIPHERGLYR1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGLYR1 
Mutations
ICGC Data PortalGLYR1 
TCGA Data PortalGLYR1 
Broad Tumor PortalGLYR1
OASIS PortalGLYR1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGLYR1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGLYR1
Mutations and Diseases : HGMDGLYR1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GLYR1
DgiDB (Drug Gene Interaction Database)GLYR1
DoCM (Curated mutations)GLYR1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GLYR1 (select a term)
intoGenGLYR1
Cancer3DGLYR1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610660   
Orphanet
DisGeNETGLYR1
MedgenGLYR1
Genetic Testing Registry GLYR1
NextProtQ49A26 [Medical]
TSGene84656
GENETestsGLYR1
Target ValidationGLYR1
Huge Navigator GLYR1 [HugePedia]
snp3D : Map Gene to Disease84656
BioCentury BCIQGLYR1
ClinGenGLYR1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84656
Chemical/Pharm GKB GenePA165450093
Clinical trialGLYR1
Miscellaneous
canSAR (ICR)GLYR1 (select the gene name)
DataMed IndexGLYR1
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGLYR1
EVEXGLYR1
GoPubMedGLYR1
iHOPGLYR1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Sep 3 15:29:51 CEST 2019
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