Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54331
MIM: 606981
HGNC: 4404
Ensembl: ENSG00000186469
Variants:
dbSNP: 54331
ClinVar: 54331
TCGA: ENSG00000186469
COSMIC: GNG2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA33384 | PLCB1 | Gene | Pathway | associated | |||
| PA33385 | PLCB2 | Gene | Pathway | associated | |||
| PA33386 | PLCB3 | Gene | Pathway | associated | |||
| PA33387 | PLCB4 | Gene | Pathway | associated | |||
| PA447199 | Bipolar Disorder | Disease | Literature, MultilinkAnnotation | associated | 24718920 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34212982 | 2021 | Interference with KCNJ2 inhibits proliferation, migration and EMT progression of apillary thyroid carcinoma cells by upregulating GNG2 expression. | 3 |
| 34212982 | 2021 | Interference with KCNJ2 inhibits proliferation, migration and EMT progression of apillary thyroid carcinoma cells by upregulating GNG2 expression. | 3 |
| 30928649 | 2019 | 3'UTR variants of TNS3, PHLDB1, NTN4, and GNG2 genes are associated with IgA nephropathy risk in Chinese Han population. | 8 |
| 31730405 | 2019 | miR-30a-GNG2 and miR-15b-ACSS2 Interaction Pairs May Be Potentially Crucial for Development of Abdominal Aortic Aneurysm by Influencing Inflammation. | 7 |
| 30928649 | 2019 | 3'UTR variants of TNS3, PHLDB1, NTN4, and GNG2 genes are associated with IgA nephropathy risk in Chinese Han population. | 8 |
| 31730405 | 2019 | miR-30a-GNG2 and miR-15b-ACSS2 Interaction Pairs May Be Potentially Crucial for Development of Abdominal Aortic Aneurysm by Influencing Inflammation. | 7 |
| 28818508 | 2017 | The role of the IL-8 signaling pathway in the infiltration of granulocytes into the livers of patients with alcoholic hepatitis. | 12 |
| 28818508 | 2017 | The role of the IL-8 signaling pathway in the infiltration of granulocytes into the livers of patients with alcoholic hepatitis. | 12 |
| 25367286 | 2015 | Alteration of gene expression profiling including GPR174 and GNG2 is associated with vasovagal syncope. | 8 |
| 25941381 | 2015 | G-protein βγ subunits are positive regulators of Kv7.4 and native vascular Kv7 channel activity. | 29 |
| 25367286 | 2015 | Alteration of gene expression profiling including GPR174 and GNG2 is associated with vasovagal syncope. | 8 |
| 25941381 | 2015 | G-protein βγ subunits are positive regulators of Kv7.4 and native vascular Kv7 channel activity. | 29 |
| 24462769 | 2014 | Gβγ interacts with mTOR and promotes its activation. | 13 |
| 24462769 | 2014 | Gβγ interacts with mTOR and promotes its activation. | 13 |
| 22957104 | 2012 | Topography of Gng2- and NetrinG2-expression suggests an insular origin of the human claustrum. | 21 |
Citation
Dessen P
GNG2 (G protein subunit gamma 2)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43293/gng2
