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GNG3 (G protein subunit gamma 3)

Identity

Alias_namesguanine nucleotide binding protein (G protein), gamma 3
Other alias-
HGNC (Hugo) GNG3
LocusID (NCBI) 2785
Atlas_Id 40731
Location 11q12.3  [Link to chromosome band 11q12]
Location_base_pair Starts at 62707594 and ends at 62709206 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GNG3   4405
Cards
Entrez_Gene (NCBI)GNG3  2785  G protein subunit gamma 3
Aliases
GeneCards (Weizmann)GNG3
Ensembl hg19 (Hinxton)ENSG00000162188 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162188 [Gene_View]  ENSG00000162188 [Sequence]  chr11:62707594-62709206 [Contig_View]  GNG3 [Vega]
ICGC DataPortalENSG00000162188
TCGA cBioPortalGNG3
AceView (NCBI)GNG3
Genatlas (Paris)GNG3
WikiGenes2785
SOURCE (Princeton)GNG3
Genetics Home Reference (NIH)GNG3
Genomic and cartography
GoldenPath hg38 (UCSC)GNG3  -     chr11:62707594-62709206 +  11q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GNG3  -     11q12.3   [Description]    (hg19-Feb_2009)
GoldenPathGNG3 - 11q12.3 [CytoView hg19]  GNG3 - 11q12.3 [CytoView hg38]
ImmunoBaseENSG00000162188
Mapping of homologs : NCBIGNG3 [Mapview hg19]  GNG3 [Mapview hg38]
OMIM608941   
Gene and transcription
Genbank (Entrez)AF075042 AF087900 AF092129 AF493871 AK311933
RefSeq transcript (Entrez)NM_012202
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GNG3
Cluster EST : UnigeneHs.740581 [ NCBI ]
CGAP (NCI)Hs.740581
Alternative Splicing GalleryENSG00000162188
Gene ExpressionGNG3 [ NCBI-GEO ]   GNG3 [ EBI - ARRAY_EXPRESS ]   GNG3 [ SEEK ]   GNG3 [ MEM ]
Gene Expression Viewer (FireBrowse)GNG3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2785
GTEX Portal (Tissue expression)GNG3
Human Protein AtlasENSG00000162188-GNG3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP63215   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP63215  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP63215
Splice isoforms : SwissVarP63215
PhosPhoSitePlusP63215
Domaine pattern : Prosite (Expaxy)G_PROTEIN_GAMMA (PS50058)   
Domains : Interpro (EBI)G-protein_gamma-like_dom    GGL_sf    Gprotein-gamma   
Domain families : Pfam (Sanger)G-gamma (PF00631)   
Domain families : Pfam (NCBI)pfam00631   
Domain families : Smart (EMBL)GGL (SM00224)  
Conserved Domain (NCBI)GNG3
DMDM Disease mutations2785
Blocks (Seattle)GNG3
SuperfamilyP63215
Human Protein Atlas [tissue]ENSG00000162188-GNG3 [tissue]
Peptide AtlasP63215
HPRD12337
IPIIPI00023625   
Protein Interaction databases
DIP (DOE-UCLA)P63215
IntAct (EBI)P63215
FunCoupENSG00000162188
BioGRIDGNG3
STRING (EMBL)GNG3
ZODIACGNG3
Ontologies - Pathways
QuickGOP63215
Ontology : AmiGOactivation of MAPK activity  GTPase activity  protein binding  heterotrimeric G-protein complex  plasma membrane  G protein-coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  postsynaptic density  dendrite  G-protein beta/gamma-subunit complex  G-protein beta-subunit binding  cell body  
Ontology : EGO-EBIactivation of MAPK activity  GTPase activity  protein binding  heterotrimeric G-protein complex  plasma membrane  G protein-coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  postsynaptic density  dendrite  G-protein beta/gamma-subunit complex  G-protein beta-subunit binding  cell body  
Pathways : KEGGRas signaling pathway    Chemokine signaling pathway    PI3K-Akt signaling pathway    Circadian entrainment    Retrograde endocannabinoid signaling    Glutamatergic synapse    Cholinergic synapse    Serotonergic synapse    GABAergic synapse    Dopaminergic synapse    Taste transduction    Morphine addiction    Alcoholism   
NDEx NetworkGNG3
Atlas of Cancer Signalling NetworkGNG3
Wikipedia pathwaysGNG3
Orthology - Evolution
OrthoDB2785
GeneTree (enSembl)ENSG00000162188
Phylogenetic Trees/Animal Genes : TreeFamGNG3
HOGENOMP63215
Homologs : HomoloGeneGNG3
Homology/Alignments : Family Browser (UCSC)GNG3
Gene fusions - Rearrangements
Fusion : QuiverGNG3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGNG3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GNG3
dbVarGNG3
ClinVarGNG3
1000_GenomesGNG3 
Exome Variant ServerGNG3
ExAC (Exome Aggregation Consortium)ENSG00000162188
GNOMAD BrowserENSG00000162188
Varsome BrowserGNG3
Genetic variants : HAPMAP2785
Genomic Variants (DGV)GNG3 [DGVbeta]
DECIPHERGNG3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGNG3 
Mutations
ICGC Data PortalGNG3 
TCGA Data PortalGNG3 
Broad Tumor PortalGNG3
OASIS PortalGNG3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGNG3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGNG3
Mutations and Diseases : HGMDGNG3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GNG3
DgiDB (Drug Gene Interaction Database)GNG3
DoCM (Curated mutations)GNG3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GNG3 (select a term)
intoGenGNG3
Cancer3DGNG3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608941   
Orphanet
DisGeNETGNG3
MedgenGNG3
Genetic Testing Registry GNG3
NextProtP63215 [Medical]
TSGene2785
GENETestsGNG3
Target ValidationGNG3
Huge Navigator GNG3 [HugePedia]
snp3D : Map Gene to Disease2785
BioCentury BCIQGNG3
ClinGenGNG3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2785
Chemical/Pharm GKB GenePA28785
Clinical trialGNG3
Miscellaneous
canSAR (ICR)GNG3 (select the gene name)
DataMed IndexGNG3
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGNG3
EVEXGNG3
GoPubMedGNG3
iHOPGNG3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 17:45:12 CET 2019

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