Atlas of Genetics and Cytogenetics in Oncology and Haematology

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GNGT2 (G protein subunit gamma transducin 2)

Identity

Alias_namesguanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
Alias_symbol (synonym)GNG9
Other aliasG-GAMMA-8
G-GAMMA-C
GNG8
GNGT8
HGNC (Hugo) GNGT2
LocusID (NCBI) 2793
Atlas_Id 43298
Location 17q21.32  [Link to chromosome band 17q21]
Location_base_pair Starts at 49206234 and ends at 49209381 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GNGT2   4412
Cards
Entrez_Gene (NCBI)GNGT2  2793  G protein subunit gamma transducin 2
AliasesG-GAMMA-8; G-GAMMA-C; GNG8; GNG9; 
GNGT8
GeneCards (Weizmann)GNGT2
Ensembl hg19 (Hinxton)ENSG00000167083 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000167083 [Gene_View]  ENSG00000167083 [Sequence]  chr17:49206234-49209381 [Contig_View]  GNGT2 [Vega]
ICGC DataPortalENSG00000167083
TCGA cBioPortalGNGT2
AceView (NCBI)GNGT2
Genatlas (Paris)GNGT2
WikiGenes2793
SOURCE (Princeton)GNGT2
Genetics Home Reference (NIH)GNGT2
Genomic and cartography
GoldenPath hg38 (UCSC)GNGT2  -     chr17:49206234-49209381 -  17q21.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GNGT2  -     17q21.32   [Description]    (hg19-Feb_2009)
GoldenPathGNGT2 - 17q21.32 [CytoView hg19]  GNGT2 - 17q21.32 [CytoView hg38]
ImmunoBaseENSG00000167083
Mapping of homologs : NCBIGNGT2 [Mapview hg19]  GNGT2 [Mapview hg38]
OMIM139391   
Gene and transcription
Genbank (Entrez)AF365870 AF493876 AI857683 AK312839 BC008663
RefSeq transcript (Entrez)NM_001198754 NM_001198755 NM_001198756 NM_031498
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GNGT2
Cluster EST : UnigeneHs.181781 [ NCBI ]
CGAP (NCI)Hs.181781
Alternative Splicing GalleryENSG00000167083
Gene ExpressionGNGT2 [ NCBI-GEO ]   GNGT2 [ EBI - ARRAY_EXPRESS ]   GNGT2 [ SEEK ]   GNGT2 [ MEM ]
Gene Expression Viewer (FireBrowse)GNGT2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2793
GTEX Portal (Tissue expression)GNGT2
Human Protein AtlasENSG00000167083-GNGT2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14610   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14610  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14610
Splice isoforms : SwissVarO14610
PhosPhoSitePlusO14610
Domaine pattern : Prosite (Expaxy)G_PROTEIN_GAMMA (PS50058)   
Domains : Interpro (EBI)G-protein_gamma-like_dom    GGL_sf    Gprotein-gamma   
Domain families : Pfam (Sanger)G-gamma (PF00631)   
Domain families : Pfam (NCBI)pfam00631   
Domain families : Smart (EMBL)GGL (SM00224)  
Conserved Domain (NCBI)GNGT2
DMDM Disease mutations2793
Blocks (Seattle)GNGT2
SuperfamilyO14610
Human Protein Atlas [tissue]ENSG00000167083-GNGT2 [tissue]
Peptide AtlasO14610
HPRD06792
IPIIPI00023032   IPI00964034   
Protein Interaction databases
DIP (DOE-UCLA)O14610
IntAct (EBI)O14610
FunCoupENSG00000167083
BioGRIDGNGT2
STRING (EMBL)GNGT2
ZODIACGNGT2
Ontologies - Pathways
QuickGOO14610
Ontology : AmiGOGTPase activity  GTPase activity  heterotrimeric G-protein complex  heterotrimeric G-protein complex  heterotrimeric G-protein complex  plasma membrane  G protein-coupled receptor signaling pathway  G protein-coupled receptor signaling pathway  phototransduction  G-protein beta/gamma-subunit complex  G-protein beta-subunit binding  
Ontology : EGO-EBIGTPase activity  GTPase activity  heterotrimeric G-protein complex  heterotrimeric G-protein complex  heterotrimeric G-protein complex  plasma membrane  G protein-coupled receptor signaling pathway  G protein-coupled receptor signaling pathway  phototransduction  G-protein beta/gamma-subunit complex  G-protein beta-subunit binding  
Pathways : KEGGRas signaling pathway    Chemokine signaling pathway    PI3K-Akt signaling pathway    Circadian entrainment    Retrograde endocannabinoid signaling    Glutamatergic synapse    Cholinergic synapse    Serotonergic synapse    GABAergic synapse    Dopaminergic synapse    Morphine addiction    Alcoholism   
NDEx NetworkGNGT2
Atlas of Cancer Signalling NetworkGNGT2
Wikipedia pathwaysGNGT2
Orthology - Evolution
OrthoDB2793
GeneTree (enSembl)ENSG00000167083
Phylogenetic Trees/Animal Genes : TreeFamGNGT2
HOGENOMO14610
Homologs : HomoloGeneGNGT2
Homology/Alignments : Family Browser (UCSC)GNGT2
Gene fusions - Rearrangements
Fusion : QuiverGNGT2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGNGT2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GNGT2
dbVarGNGT2
ClinVarGNGT2
1000_GenomesGNGT2 
Exome Variant ServerGNGT2
ExAC (Exome Aggregation Consortium)ENSG00000167083
GNOMAD BrowserENSG00000167083
Varsome BrowserGNGT2
Genetic variants : HAPMAP2793
Genomic Variants (DGV)GNGT2 [DGVbeta]
DECIPHERGNGT2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGNGT2 
Mutations
ICGC Data PortalGNGT2 
TCGA Data PortalGNGT2 
Broad Tumor PortalGNGT2
OASIS PortalGNGT2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGNGT2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGNGT2
Mutations and Diseases : HGMDGNGT2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GNGT2
DgiDB (Drug Gene Interaction Database)GNGT2
DoCM (Curated mutations)GNGT2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GNGT2 (select a term)
intoGenGNGT2
Cancer3DGNGT2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM139391   
Orphanet
DisGeNETGNGT2
MedgenGNGT2
Genetic Testing Registry GNGT2
NextProtO14610 [Medical]
TSGene2793
GENETestsGNGT2
Target ValidationGNGT2
Huge Navigator GNGT2 [HugePedia]
snp3D : Map Gene to Disease2793
BioCentury BCIQGNGT2
ClinGenGNGT2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2793
Chemical/Pharm GKB GenePA28791
Clinical trialGNGT2
Miscellaneous
canSAR (ICR)GNGT2 (select the gene name)
DataMed IndexGNGT2
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGNGT2
EVEXGNGT2
GoPubMedGNGT2
iHOPGNGT2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 17:45:13 CET 2019
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