GNPDA2 (glucosamine-6-phosphate deaminase 2)

2014-11-01 Affiliation

Identity

HGNC

GNPDA2

LOCATION

4p12

LOCUSID

132789

ALIAS

GNP2,SB52

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 132789
MIM: 613222
HGNC: 21526
Ensembl: ENSG00000163281

Variants:

dbSNP: 132789
ClinVar: 132789
TCGA: ENSG00000163281
COSMIC: GNPDA2

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000163281	ENST00000295448	Q8TDQ7
ENSG00000163281	ENST00000295448	A0A024R9X5
ENSG00000163281	ENST00000507534	Q8TDQ7
ENSG00000163281	ENST00000507917	Q8TDQ7
ENSG00000163281	ENST00000509756	Q8TDQ7
ENSG00000163281	ENST00000608855	V9GYW0
ENSG00000163281	ENST00000609092	V9GYK3

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Amino sugar and nucleotide sugar metabolism	KEGG	ko00520
Amino sugar and nucleotide sugar metabolism	KEGG	hsa00520
Metabolic pathways	KEGG	hsa01100
Metabolism	REACTOME	R-HSA-1430728
Metabolism of carbohydrates	REACTOME	R-HSA-71387
Glucose metabolism	REACTOME	R-HSA-70326

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
19079261	2009	Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.	700
19164386	2009	Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden.	104
19692490	2009	Obesity genes identified in genome-wide association studies are associated with adiposity measures and potentially with nutrient-specific food preference.	77
19812171	2010	Cumulative effects and predictive value of common obesity-susceptibility variants identified by genome-wide association studies.	74
20520848	2010	Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth.	70
20724581	2010	Genetic susceptibility to obesity and related traits in childhood and adolescence: influence of loci identified by genome-wide association studies.	47
20215397	2010	Implication of genetic variants near NEGR1, SEC16B, TMEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, and KCTD15 with obesity and type 2 diabetes in 7705 Chinese.	44
20816195	2010	Analyses of shared genetic factors between asthma and obesity in children.	43
19851340	2009	Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population.	37
19851340	2009	Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population.	37

Citation

Dessen P

GNPDA2 (glucosamine-6-phosphate deaminase 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63866/gnpda2