GNPNAT1 (glucosamine-phosphate N-acetyltransferase 1)

2017-08-01  

Identity

HGNC
LOCATION
14q22.1
LOCUSID
ALIAS
GNA1,GNPNAT,Gpnat1
FUSION GENES

Other Information

Locus ID:

NCBI: 64841
MIM: 616510
HGNC: 19980
Ensembl: ENSG00000100522

Variants:

dbSNP: 64841
ClinVar: 64841
TCGA: ENSG00000100522
COSMIC: GNPNAT1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100522ENST00000216410Q96EK6
ENSG00000100522ENST00000216410A0A024R649
ENSG00000100522ENST00000554230G3V5E4
ENSG00000100522ENST00000557604G3V4W4
ENSG00000100522ENST00000650397Q96EK6
ENSG00000100522ENST00000650397A0A024R649

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Amino sugar and nucleotide sugar metabolismKEGGko00520
Amino sugar and nucleotide sugar metabolismKEGGhsa00520
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Asparagine N-linked glycosylationREACTOMER-HSA-446203
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent proteinREACTOMER-HSA-446193
Synthesis of substrates in N-glycan biosythesisREACTOMER-HSA-446219
Synthesis of UDP-N-acetyl-glucosamineREACTOMER-HSA-446210

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
186758102008Acceptor substrate binding revealed by crystal structure of human glucosamine-6-phosphate N-acetyltransferase 1.10
269356562016Human acetyl-CoA:glucosamine-6-phosphate N-acetyltransferase 1 has a relaxed donor specificity and transfers acyl groups up to four carbons in length.1

Citation

Dessen P

GNPNAT1 (glucosamine-phosphate N-acetyltransferase 1)

Atlas Genet Cytogenet Oncol Haematol. 2017-08-01

Online version: http://atlasgeneticsoncology.org/gene/56977/gnpnat1