Identity
HGNC
LOCATION
17p13.2
LOCUSID
ALIAS
BDPLT1,BDPLT3,BSS,CD42B,CD42b-alpha,DBPLT3,GP1B,GPIbA,GPIbalpha,VWDP
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2811
MIM: 606672
HGNC: 4439
Ensembl: ENSG00000185245
Variants:
dbSNP: 2811
ClinVar: 2811
TCGA: ENSG00000185245
COSMIC: GP1BA
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000185245 | ENST00000329125 | P07359 |
| ENSG00000185245 | ENST00000611961 | A0A0C4DGZ8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA448497 | aspirin | Chemical | ClinicalAnnotation | associated | PD | 17245331, 18417193 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37922495 | 2024 | GPIbα-filamin A interaction regulates megakaryocyte localization and budding during platelet biogenesis. | 3 |
| 37922495 | 2024 | GPIbα-filamin A interaction regulates megakaryocyte localization and budding during platelet biogenesis. | 3 |
| 36740532 | 2023 | Comprehensive analysis of platelet glycoprotein Ibα ectodomain glycosylation. | 9 |
| 36809953 | 2023 | Integrated Proteomics and Metabolomics Analyses of Serum in Chinese Patients with Severe and Active Graves' Orbitopathy: A Cross-sectional Study. | 0 |
| 37044132 | 2023 | Low α-Thrombin/GPIbα Interaction Is a Potential Contributor to Platelet Hyper-reactivity in COVID-19 Patients. | 1 |
| 36740532 | 2023 | Comprehensive analysis of platelet glycoprotein Ibα ectodomain glycosylation. | 9 |
| 36809953 | 2023 | Integrated Proteomics and Metabolomics Analyses of Serum in Chinese Patients with Severe and Active Graves' Orbitopathy: A Cross-sectional Study. | 0 |
| 37044132 | 2023 | Low α-Thrombin/GPIbα Interaction Is a Potential Contributor to Platelet Hyper-reactivity in COVID-19 Patients. | 1 |
| 35055070 | 2022 | A GP1BA Variant in a Czech Family with Monoallelic Bernard-Soulier Syndrome. | 0 |
| 36173017 | 2022 | Biological, clinical features and modelling of heterozygous variants of glycoprotein Ib platelet subunit alpha (GP1BA) and glycoprotein Ib platelet subunit beta (GP1BB) genes responsible for constitutional thrombocytopenia. | 1 |
| 35055070 | 2022 | A GP1BA Variant in a Czech Family with Monoallelic Bernard-Soulier Syndrome. | 0 |
| 36173017 | 2022 | Biological, clinical features and modelling of heterozygous variants of glycoprotein Ib platelet subunit alpha (GP1BA) and glycoprotein Ib platelet subunit beta (GP1BB) genes responsible for constitutional thrombocytopenia. | 1 |
| 33220290 | 2021 | Increased circulating CD31+/CD42b-EMPs in Perthes disease and inhibit HUVECs angiogenesis via endothelial dysfunction. | 8 |
| 33548391 | 2021 | A fibrinolytic snake venom metalloproteinase, mutalysin-II, with antiplatelet activity and targeting capability toward glycoprotein GPIbα and glycoprotein GPVI. | 5 |
| 33906312 | 2021 | Predictive Value of Kozak Gene Polymorphism for Thrombosis in Patients with Philadelphia-Negative MPNs. | 1 |
Citation
Dessen P
GP1BA (glycoprotein Ib platelet subunit alpha)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46312/gp1ba
