GP2 (glycoprotein 2)

2011-04-01  

Identity

HGNC
LOCATION
16p12.3
LOCUSID
ALIAS
ZAP75

Other Information

Locus ID:

NCBI: 2813
MIM: 602977
HGNC: 4441
Ensembl: ENSG00000169347

Variants:

dbSNP: 2813
ClinVar: 2813
TCGA: ENSG00000169347
COSMIC: GP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000169347ENST00000302555P55259
ENSG00000169347ENST00000341642P55259
ENSG00000169347ENST00000381360P55259
ENSG00000169347ENST00000381362P55259
ENSG00000169347ENST00000572347I3L4Y3
ENSG00000169347ENST00000572478I3L486
ENSG00000169347ENST00000574982I3L324
ENSG00000169347ENST00000575449I3L2Z7
ENSG00000169347ENST00000575582I3L3I2

Expression (GTEx)

0
5000
10000
15000

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Post-translational modification: synthesis of GPI-anchored proteinsREACTOMER-HSA-163125

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
199074952009Uptake through glycoprotein 2 of FimH(+) bacteria by M cells initiates mucosal immune response.170
288357092017Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors.20
196276152009The pancreatic zymogen granule membrane protein, GP2, binds Escherichia coli Type 1 fimbriae.18
231187802012Ileal inflammation may trigger the development of GP2-specific pancreatic autoantibodies in patients with Crohn's disease.16
211906812011The zymogen granule protein 2 (GP2) binds to scavenger receptor expressed on endothelial cells I (SREC-I).15
228912852012Identification of pancreatic glycoprotein 2 as an endogenous immunomodulator of innate and adaptive immune responses.15
259685832015Rediscovery of the Anti-Pancreatic Antibodies and Evaluation of their Prognostic Value in a Prospective Clinical Cohort of Crohn's Patients: The Importance of Specific Target Antigens [GP2 and CUZD1].14
199199032010The c.1275A>G putative chronic pancreatitis-associated synonymous polymorphism in the glycoprotein 2 (GP2) gene decreases exon 9 inclusion.4
203357792010Genetic analysis of the glycoprotein 2 gene in patients with chronic pancreatitis.4
203357792010Genetic analysis of the glycoprotein 2 gene in patients with chronic pancreatitis.4

Citation

Dessen P

GP2 (glycoprotein 2)

Atlas Genet Cytogenet Oncol Haematol. 2011-04-01

Online version: http://atlasgeneticsoncology.org/gene/52181/gp2