GPR101 (G protein-coupled receptor 101)

2016-08-01  

Identity

HGNC
LOCATION
Xq26.3
LOCUSID
ALIAS
GPCR6,PAGH2,PITA2

Other Information

Locus ID:

NCBI: 83550
MIM: 300393
HGNC: 14963
Ensembl: ENSG00000165370

Variants:

dbSNP: 83550
ClinVar: 83550
TCGA: ENSG00000165370
COSMIC: GPR101

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000165370ENST00000298110Q96P66
ENSG00000165370ENST00000651716Q96P66

Expression (GTEx)

0
1
2
3
4
5

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
254705692014Gigantism and acromegaly due to Xq26 microduplications and GPR101 mutation.51
272456632016Germline or somatic GPR101 duplication leads to X-linked acrogigantism: a clinico-pathological and genetic study.11
267929342016Very low frequency of germline GPR101 genetic variation and no biallelic defects with AIP in a large cohort of patients with sporadic pituitary adenomas.10
242645762014GnRH-(1-5) transactivates EGFR in Ishikawa human endometrial cells via an orphan G protein-coupled receptor.9
268159032016Analysis of GPR101 and AIP genes mutations in acromegaly: a multicentric study.4
272825442016Characterization of GPR101 transcript structure and expression patterns.3
296782812018An orphan G-protein-coupled receptor causes human gigantism and/or acromegaly: Molecular biology and clinical correlations.3
267978722016GPR101 Mutations are not a Frequent Cause of Congenital Isolated Growth Hormone Deficiency.2
307110292019Mutations in GPR101 as a potential cause of X-linked acrogigantism and acromegaly.1

Citation

Dessen P

GPR101 (G protein-coupled receptor 101)

Atlas Genet Cytogenet Oncol Haematol. 2016-08-01

Online version: http://atlasgeneticsoncology.org/gene/55842/gpr101