GPR12 (G protein-coupled receptor 12)

2016-10-01  

Identity

HGNC
GPR12
LOCATION
13q12.13
LOCUSID
2835
ALIAS
GPCR12,GPCR21,PPP1R84

Other Information

Locus ID:

NCBI: 2835
MIM: 600752
HGNC: 4466
Ensembl: ENSG00000132975

Variants:

dbSNP: 2835
ClinVar: 2835
TCGA: ENSG00000132975
COSMIC: GPR12

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132975ENST00000381436P47775
ENSG00000132975ENST00000381436A8K2F5
ENSG00000132975ENST00000405846P47775
ENSG00000132975ENST00000405846A8K2F5

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
126495922003Fluid shear stress differentially regulates gpr3, gpr6, and gpr12 expression in human umbilical vein endothelial cells.8
224309502012Involvement of GPR12 in the regulation of cell proliferation and survival.7
288889842017Cannabidiol, a novel inverse agonist for GPR12.7

Citation

Dessen P

GPR12 (G protein-coupled receptor 12)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56043/gpr12