GPR135 (G protein-coupled receptor 135)

2017-11-01  

Identity

HGNC
GPR135
LOCATION
14q23.1
LOCUSID
64582
ALIAS
HUMNPIIY20

Other Information

Locus ID:

NCBI: 64582
MIM: 607970
HGNC: 19991
Ensembl: ENSG00000181619

Variants:

dbSNP: 64582
ClinVar: 64582
TCGA: ENSG00000181619
COSMIC: GPR135

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000181619ENST00000395116Q8IZ08
ENSG00000181619ENST00000481661Q8IZ08

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
201983152010Association of genetic variants with hemorrhagic stroke in Japanese individuals.11
287227702017Asbestos-associated genome-wide DNA methylation changes in lung cancer.11
288275382017Orphan GPR61, GPR62 and GPR135 receptors and the melatonin MT2 receptor reciprocally modulate their signaling functions.2

Citation

Dessen P

GPR135 (G protein-coupled receptor 135)

Atlas Genet Cytogenet Oncol Haematol. 2017-11-01

Online version: http://atlasgeneticsoncology.org/gene/57228/gpr135