Atlas of Genetics and Cytogenetics in Oncology and Haematology

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GPR158 (G protein-coupled receptor 158)

Identity

Alias_symbol (synonym)KIAA1136
Other alias-
HGNC (Hugo) GPR158
LocusID (NCBI) 57512
Atlas_Id 54344
Location 10p12.1  [Link to chromosome band 10p12]
Location_base_pair Starts at 25175361 and ends at 25602228 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GPR158 (10p12.1) / MYO16 (13q33.3)MALRD1 (10p12.31) / GPR158 (10p12.1)WAC (10p12.1) / GPR158 (10p12.1)
C10orf112 GPR158 10p12.1GPR158 10p12.1 / MYO16 13q33.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 5 ]
  Lung: Translocations in Small Cell Carcinoma
ARHGAP21/GPR158 (10p12)
MALRD1/GPR158 (10p12)
WAC/GPR158 (10p12)
t(10;13)(p12;q33) GPR158/MYO16

External links

Nomenclature
HGNC (Hugo)GPR158   23689
Cards
Entrez_Gene (NCBI)GPR158  57512  G protein-coupled receptor 158
Aliases
GeneCards (Weizmann)GPR158
Ensembl hg19 (Hinxton)ENSG00000151025 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000151025 [Gene_View]  ENSG00000151025 [Sequence]  chr10:25175361-25602228 [Contig_View]  GPR158 [Vega]
ICGC DataPortalENSG00000151025
TCGA cBioPortalGPR158
AceView (NCBI)GPR158
Genatlas (Paris)GPR158
WikiGenes57512
SOURCE (Princeton)GPR158
Genetics Home Reference (NIH)GPR158
Genomic and cartography
GoldenPath hg38 (UCSC)GPR158  -     chr10:25175361-25602228 +  10p12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPR158  -     10p12.1   [Description]    (hg19-Feb_2009)
GoldenPathGPR158 - 10p12.1 [CytoView hg19]  GPR158 - 10p12.1 [CytoView hg38]
ImmunoBaseENSG00000151025
Mapping of homologs : NCBIGPR158 [Mapview hg19]  GPR158 [Mapview hg38]
OMIM614573   
Gene and transcription
Genbank (Entrez)AB032962 AK095120 AY528411
RefSeq transcript (Entrez)NM_020752
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GPR158
Cluster EST : UnigeneHs.499108 [ NCBI ]
CGAP (NCI)Hs.499108
Alternative Splicing GalleryENSG00000151025
Gene ExpressionGPR158 [ NCBI-GEO ]   GPR158 [ EBI - ARRAY_EXPRESS ]   GPR158 [ SEEK ]   GPR158 [ MEM ]
Gene Expression Viewer (FireBrowse)GPR158 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57512
GTEX Portal (Tissue expression)GPR158
Human Protein AtlasENSG00000151025-GPR158 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5T848   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5T848  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5T848
Splice isoforms : SwissVarQ5T848
PhosPhoSitePlusQ5T848
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F3_4 (PS50259)   
Domains : Interpro (EBI)GPCR_3_C   
Domain families : Pfam (Sanger)7tm_3 (PF00003)   
Domain families : Pfam (NCBI)pfam00003   
Conserved Domain (NCBI)GPR158
DMDM Disease mutations57512
Blocks (Seattle)GPR158
SuperfamilyQ5T848
Human Protein Atlas [tissue]ENSG00000151025-GPR158 [tissue]
Peptide AtlasQ5T848
HPRD13601
IPIIPI00412541   
Protein Interaction databases
DIP (DOE-UCLA)Q5T848
IntAct (EBI)Q5T848
FunCoupENSG00000151025
BioGRIDGPR158
STRING (EMBL)GPR158
ZODIACGPR158
Ontologies - Pathways
QuickGOQ5T848
Ontology : AmiGOG protein-coupled receptor activity  plasma membrane  G protein-coupled receptor signaling pathway  integral component of membrane  protein localization to plasma membrane  
Ontology : EGO-EBIG protein-coupled receptor activity  plasma membrane  G protein-coupled receptor signaling pathway  integral component of membrane  protein localization to plasma membrane  
NDEx NetworkGPR158
Atlas of Cancer Signalling NetworkGPR158
Wikipedia pathwaysGPR158
Orthology - Evolution
OrthoDB57512
GeneTree (enSembl)ENSG00000151025
Phylogenetic Trees/Animal Genes : TreeFamGPR158
HOGENOMQ5T848
Homologs : HomoloGeneGPR158
Homology/Alignments : Family Browser (UCSC)GPR158
Gene fusions - Rearrangements
Fusion : MitelmanGPR158/MYO16 [10p12.1/13q33.3]  
Fusion : MitelmanMALRD1/GPR158 [10p12.31/10p12.1]  [t(10;10)(p12;p12)]  
Fusion : MitelmanWAC/GPR158 [10p12.1/10p12.1]  [t(10;10)(p12;p12)]  
Fusion PortalC10orf112 GPR158 10p12.1 LUAD
Fusion PortalGPR158 10p12.1 MYO16 13q33.3 BRCA
Fusion : QuiverGPR158
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPR158 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPR158
dbVarGPR158
ClinVarGPR158
1000_GenomesGPR158 
Exome Variant ServerGPR158
ExAC (Exome Aggregation Consortium)ENSG00000151025
GNOMAD BrowserENSG00000151025
Varsome BrowserGPR158
Genetic variants : HAPMAP57512
Genomic Variants (DGV)GPR158 [DGVbeta]
DECIPHERGPR158 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPR158 
Mutations
ICGC Data PortalGPR158 
TCGA Data PortalGPR158 
Broad Tumor PortalGPR158
OASIS PortalGPR158 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPR158  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGPR158
Mutations and Diseases : HGMDGPR158
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GPR158
DgiDB (Drug Gene Interaction Database)GPR158
DoCM (Curated mutations)GPR158 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPR158 (select a term)
intoGenGPR158
Cancer3DGPR158(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614573   
Orphanet
DisGeNETGPR158
MedgenGPR158
Genetic Testing Registry GPR158
NextProtQ5T848 [Medical]
TSGene57512
GENETestsGPR158
Target ValidationGPR158
Huge Navigator GPR158 [HugePedia]
snp3D : Map Gene to Disease57512
BioCentury BCIQGPR158
ClinGenGPR158
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57512
Chemical/Pharm GKB GenePA134939018
Clinical trialGPR158
Miscellaneous
canSAR (ICR)GPR158 (select the gene name)
DataMed IndexGPR158
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPR158
EVEXGPR158
GoPubMedGPR158
iHOPGPR158
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 13 17:45:29 CET 2019
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