Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

GPS1 (G protein pathway suppressor 1)

Identity

Other namesCOPS1
CSN1
SGN1
HGNC (Hugo) GPS1
LocusID (NCBI) 2873
Atlas_Id 47118
Location 17q25.3  [Link to chromosome band 17q25]
Location_base_pair Starts at 80009763 and ends at 80015346 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
SPTAN1 (9q34.11) / GPS1 (17q25.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GPS1   4549
Cards
Entrez_Gene (NCBI)GPS1  2873  G protein pathway suppressor 1
AliasesCOPS1; CSN1; SGN1
GeneCards (Weizmann)GPS1
Ensembl hg19 (Hinxton)ENSG00000169727 [Gene_View]  chr17:80009763-80015346 [Contig_View]  GPS1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000169727 [Gene_View]  chr17:80009763-80015346 [Contig_View]  GPS1 [Vega]
ICGC DataPortalENSG00000169727
TCGA cBioPortalGPS1
AceView (NCBI)GPS1
Genatlas (Paris)GPS1
WikiGenes2873
SOURCE (Princeton)GPS1
Genomic and cartography
GoldenPath hg19 (UCSC)GPS1  -     chr17:80009763-80015346 +  17q25.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GPS1  -     17q25.3   [Description]    (hg38-Dec_2013)
EnsemblGPS1 - 17q25.3 [CytoView hg19]  GPS1 - 17q25.3 [CytoView hg38]
Mapping of homologs : NCBIGPS1 [Mapview hg19]  GPS1 [Mapview hg38]
OMIM601934   
Gene and transcription
Genbank (Entrez)AB209596 AK026610 AK093283 AK222508 AK225248
RefSeq transcript (Entrez)NM_001321089 NM_001321090 NM_001321091 NM_001321092 NM_001321093 NM_004127 NM_212492
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010663 NW_004929408
Consensus coding sequences : CCDS (NCBI)GPS1
Cluster EST : UnigeneHs.268530 [ NCBI ]
CGAP (NCI)Hs.268530
Alternative Splicing GalleryENSG00000169727
Gene ExpressionGPS1 [ NCBI-GEO ]   GPS1 [ EBI - ARRAY_EXPRESS ]   GPS1 [ SEEK ]   GPS1 [ MEM ]
Gene Expression Viewer (FireBrowse)GPS1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2873
GTEX Portal (Tissue expression)GPS1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13098 (Uniprot)
NextProtQ13098  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13098
Splice isoforms : SwissVarQ13098 (Swissvar)
PhosPhoSitePlusQ13098
Domains : Interpro (EBI)CSN1    PCI_dom    Rpn7/CSN1    TPR-like_helical_dom    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)PCI (PF01399)    RPN7 (PF10602)   
Domain families : Pfam (NCBI)pfam01399    pfam10602   
Domain families : Smart (EMBL)PINT (SM00088)  
DMDM Disease mutations2873
Blocks (Seattle)GPS1
PDB (SRS)4D10    4D18    4WSN   
PDB (PDBSum)4D10    4D18    4WSN   
PDB (IMB)4D10    4D18    4WSN   
PDB (RSDB)4D10    4D18    4WSN   
Structural Biology KnowledgeBase4D10    4D18    4WSN   
SCOP (Structural Classification of Proteins)4D10    4D18    4WSN   
CATH (Classification of proteins structures)4D10    4D18    4WSN   
SuperfamilyQ13098
Human Protein AtlasENSG00000169727
Peptide AtlasQ13098
HPRD15991
IPIIPI00156282   IPI00921488   IPI00414289   IPI00300386   IPI00556522   
Protein Interaction databases
DIP (DOE-UCLA)Q13098
IntAct (EBI)Q13098
FunCoupENSG00000169727
BioGRIDGPS1
STRING (EMBL)GPS1
ZODIACGPS1
Ontologies - Pathways
QuickGOQ13098
Ontology : AmiGOinactivation of MAPK activity  nucleotide-excision repair, DNA damage recognition  GTPase inhibitor activity  protein binding  nucleoplasm  cytoplasm  transcription-coupled nucleotide-excision repair  cell cycle  JNK cascade  COP9 signalosome  COP9 signalosome assembly  cullin deneddylation  negative regulation of GTPase activity  
Ontology : EGO-EBIinactivation of MAPK activity  nucleotide-excision repair, DNA damage recognition  GTPase inhibitor activity  protein binding  nucleoplasm  cytoplasm  transcription-coupled nucleotide-excision repair  cell cycle  JNK cascade  COP9 signalosome  COP9 signalosome assembly  cullin deneddylation  negative regulation of GTPase activity  
NDEx Network
Atlas of Cancer Signalling NetworkGPS1
Wikipedia pathwaysGPS1
Orthology - Evolution
OrthoDB2873
GeneTree (enSembl)ENSG00000169727
Phylogenetic Trees/Animal Genes : TreeFamGPS1
Homologs : HomoloGeneGPS1
Homology/Alignments : Family Browser (UCSC)GPS1
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerGPS1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPS1
dbVarGPS1
ClinVarGPS1
1000_GenomesGPS1 
Exome Variant ServerGPS1
ExAC (Exome Aggregation Consortium)GPS1 (select the gene name)
Genetic variants : HAPMAP2873
Genomic Variants (DGV)GPS1 [DGVbeta]
Mutations
ICGC Data PortalGPS1 
TCGA Data PortalGPS1 
Broad Tumor PortalGPS1
OASIS PortalGPS1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPS1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GPS1
DgiDB (Drug Gene Interaction Database)GPS1
DoCM (Curated mutations)GPS1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPS1 (select a term)
intoGenGPS1
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)17:80009763-80015346  ENSG00000169727
CONAN: Copy Number AnalysisGPS1 
Mutations and Diseases : HGMDGPS1
OMIM601934   
MedgenGPS1
Genetic Testing Registry GPS1
NextProtQ13098 [Medical]
TSGene2873
GENETestsGPS1
Huge Navigator GPS1 [HugePedia]
snp3D : Map Gene to Disease2873
BioCentury BCIQGPS1
ClinGenGPS1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2873
Chemical/Pharm GKB GenePA28944
Clinical trialGPS1
Miscellaneous
canSAR (ICR)GPS1 (select the gene name)
Probes
Litterature
PubMed68 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPS1
EVEXGPS1
GoPubMedGPS1
iHOPGPS1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 9 19:03:23 CEST 2016

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.