GPSM3 (G protein signaling modulator 3)

2014-11-01 Affiliation

Identity

HGNC

GPSM3

LOCATION

6p21.32

LOCUSID

63940

ALIAS

AGS4,C6orf9,G18,G18.1a,G18.1b,G18.2,NG1

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 63940
MIM: 618558
HGNC: 13945
Ensembl: ENSG00000213654

Variants:

dbSNP: 63940
ClinVar: 63940
TCGA: ENSG00000213654
COSMIC: GPSM3

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000213654	ENST00000375040	Q9Y4H4
ENSG00000213654	ENST00000375040	A0A024RCP6
ENSG00000213654	ENST00000375043	Q9Y4H4
ENSG00000213654	ENST00000375043	A0A024RCP6
ENSG00000213654	ENST00000472768	E9PIE9
ENSG00000213654	ENST00000487761	E9PIP3
ENSG00000213654	ENST00000619085	Q9Y4H5

Expression (GTEx)

100

200

300

400

500

600

700

800

900

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
19913121	2009	Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.	85
19851445	2009	High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.	51
14656218	2004	Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif.	26
20452976	2010	Receptor-regulated interaction of activator of G-protein signaling-4 and Galphai.	26
19659809	2009	Confirmation of the novel association at the BTNL2 locus with ulcerative colitis.	15
20628086	2010	Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.	11
25271165	2014	G Protein signaling modulator-3 inhibits the inflammasome activity of NLRP3.	11
22167191	2012	G-protein signaling modulator-3 regulates heterotrimeric G-protein dynamics through dual association with Gβ and Gαi protein subunits.	9
22843681	2012	Regulation of the subcellular localization of the G-protein subunit regulator GPSM3 through direct association with 14-3-3 protein.	6
26821282	2016	Genetic variations in GPSM3 associated with protection from rheumatoid arthritis affect its transcript abundance.	4

Citation

Dessen P

GPSM3 (G protein signaling modulator 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64022/gpsm3