Identity
HGNC
LOCATION
14q23.3
LOCUSID
ALIAS
GI-GPx,GPRP,GPRP-2,GPx-2,GPx-GI,GSHPX-GI,GSHPx-2
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2877
MIM: 138319
HGNC: 4554
Ensembl: ENSG00000176153
Variants:
dbSNP: 2877
ClinVar: 2877
TCGA: ENSG00000176153
COSMIC: GPX2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36796200 | 2023 | Glutathione peroxidase 2: A key factor in the development of microsatellite instability in colon cancer. | 1 |
| 37138031 | 2023 | Glutathione peroxidase 2 knockdown suppresses gastric cancer progression and metastasis via regulation of kynurenine metabolism. | 4 |
| 37743483 | 2023 | ACVRL1 drives resistance to multitarget tyrosine kinase inhibitors in colorectal cancer by promoting USP15-mediated GPX2 stabilization. | 0 |
| 37810778 | 2023 | Long non-coding RNA NMRAL2P promotes glycolysis and reduces ROS in head and neck tumors by interacting with the ENO1 protein and promoting GPX2 transcription. | 0 |
| 36796200 | 2023 | Glutathione peroxidase 2: A key factor in the development of microsatellite instability in colon cancer. | 1 |
| 37138031 | 2023 | Glutathione peroxidase 2 knockdown suppresses gastric cancer progression and metastasis via regulation of kynurenine metabolism. | 4 |
| 37743483 | 2023 | ACVRL1 drives resistance to multitarget tyrosine kinase inhibitors in colorectal cancer by promoting USP15-mediated GPX2 stabilization. | 0 |
| 37810778 | 2023 | Long non-coding RNA NMRAL2P promotes glycolysis and reduces ROS in head and neck tumors by interacting with the ENO1 protein and promoting GPX2 transcription. | 0 |
| 34954079 | 2022 | Iron-mediated epigenetic activation of NRF2 targets. | 11 |
| 35193955 | 2022 | Redox signaling by glutathione peroxidase 2 links vascular modulation to metabolic plasticity of breast cancer. | 22 |
| 36222298 | 2022 | Glutathione peroxidase 2 overexpression promotes malignant progression and cisplatin resistance of KRAS‑mutated lung cancer cells. | 8 |
| 34954079 | 2022 | Iron-mediated epigenetic activation of NRF2 targets. | 11 |
| 35193955 | 2022 | Redox signaling by glutathione peroxidase 2 links vascular modulation to metabolic plasticity of breast cancer. | 22 |
| 36222298 | 2022 | Glutathione peroxidase 2 overexpression promotes malignant progression and cisplatin resistance of KRAS‑mutated lung cancer cells. | 8 |
| 33622868 | 2021 | Reduced Expression Level of GPX2 in T1 Bladder Cancer and its Role in Early-phase Invasion of Bladder Cancer. | 4 |
Citation
Dessen P
GPX2 (glutathione peroxidase 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45718/gpx2
