Identity
HGNC
LOCATION
11q14.2
LOCUSID
ALIAS
GPRC1E,MGLUR5,PPP1R86,mGlu5
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2915
MIM: 604102
HGNC: 4597
Ensembl: ENSG00000168959
Variants:
dbSNP: 2915
ClinVar: 2915
TCGA: ENSG00000168959
COSMIC: GRM5
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38217040 | 2024 | Metabotropic glutamate receptor 5 (mGluR5) is associated with neurodegeneration and amyloid deposition in Alzheimer's disease: A [(18)F]PSS232 PET/MRI study. | 1 |
| 38369690 | 2024 | Voltage tunes mGlu(5) receptor function, impacting synaptic transmission. | 1 |
| 38632403 | 2024 | Stepwise activation of a metabotropic glutamate receptor. | 0 |
| 38876317 | 2024 | Deficits in prefrontal metabotropic glutamate receptor 5 are associated with functional alterations during emotional processing in bipolar disorder. | 0 |
| 38217040 | 2024 | Metabotropic glutamate receptor 5 (mGluR5) is associated with neurodegeneration and amyloid deposition in Alzheimer's disease: A [(18)F]PSS232 PET/MRI study. | 1 |
| 38369690 | 2024 | Voltage tunes mGlu(5) receptor function, impacting synaptic transmission. | 1 |
| 38632403 | 2024 | Stepwise activation of a metabotropic glutamate receptor. | 0 |
| 38876317 | 2024 | Deficits in prefrontal metabotropic glutamate receptor 5 are associated with functional alterations during emotional processing in bipolar disorder. | 0 |
| 36842305 | 2023 | Inhibition of mGluR5 ameliorates lipid accumulation and inflammation in HepG2 cells. | 0 |
| 37487948 | 2023 | Upregulation of Parkinson's disease-associated protein alpha-synuclein suppresses tumorigenesis via interaction with mGluR5 and gamma-synuclein in liver cancer. | 2 |
| 38146365 | 2023 | Blockade of mGluR5 in astrocytes derived from human iPSCs modulates astrocytic function and increases phagocytosis. | 1 |
| 36842305 | 2023 | Inhibition of mGluR5 ameliorates lipid accumulation and inflammation in HepG2 cells. | 0 |
| 37487948 | 2023 | Upregulation of Parkinson's disease-associated protein alpha-synuclein suppresses tumorigenesis via interaction with mGluR5 and gamma-synuclein in liver cancer. | 2 |
| 38146365 | 2023 | Blockade of mGluR5 in astrocytes derived from human iPSCs modulates astrocytic function and increases phagocytosis. | 1 |
| 34516293 | 2022 | Noncanonical Metabotropic Glutamate Receptor 5 Signaling in Alzheimer's Disease. | 26 |
Citation
Dessen P
GRM5 (glutamate metabotropic receptor 5)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43586/grm5
