GSC (goosecoid homeobox)

2007-02-01  

Identity

HGNC
LOCATION
14q32.13
LOCUSID
ALIAS
SAMS

Other Information

Locus ID:

NCBI: 145258
MIM: 138890
HGNC: 4612
Ensembl: ENSG00000133937

Variants:

dbSNP: 145258
ClinVar: 145258
TCGA: ENSG00000133937
COSMIC: GSC

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000133937ENST00000238558P56915

Expression (GTEx)

0
5
10
15

References

Pubmed IDYearTitleCitations
171423182006The Spemann organizer gene, Goosecoid, promotes tumor metastasis.87
198756142010A genome-wide association study identifies a novel major locus for glycemic control in type 1 diabetes, as measured by both A1C and glucose.47
221781552012EVEN-SKIPPED HOMEOBOX 1 controls human ES cell differentiation by directly repressing GOOSECOID expression.16
242903752013SAMS, a syndrome of short stature, auditory-canal atresia, mandibular hypoplasia, and skeletal abnormalities is a unique neurocristopathy caused by mutations in Goosecoid.13
277057852016DIGIT Is a Conserved Long Noncoding RNA that Regulates GSC Expression to Control Definitive Endoderm Differentiation of Embryonic Stem Cells.11
199352992009Environmental and genetic factors associated with congenital microtia: a case-control study in Jiangsu, China, 2004 to 2007.10
248585672014Overexpression of goosecoid homeobox is associated with chemoresistance and poor prognosis in ovarian carcinoma.10
253433362014Goosecoid promotes the metastasis of hepatocellular carcinoma by modulating the epithelial-mesenchymal transition.9
180743792008A child with deletion (14)(q24.3q32.13) and auditory neuropathy.5
212948702011Evaluation of four novel genetic variants affecting hemoglobin A1c levels in a population-based type 2 diabetes cohort (the HUNT2 study).5

Citation

Dessen P

GSC (goosecoid homeobox)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46257/gsc