| Nomenclature |
HGNC (Hugo) | GTF2H3 4657 |
| Cards |
Entrez_Gene (NCBI) | GTF2H3 2967 general transcription factor IIH subunit 3 |
Aliases | BTF2; P34; TFB4; TFIIH |
GeneCards (Weizmann) | GTF2H3 |
Ensembl hg19 (Hinxton) | ENSG00000111358 [Gene_View] |
Ensembl hg38 (Hinxton) | ENSG00000111358 [Gene_View]  ENSG00000111358 [Sequence] chr12:123633739-123662604 [Contig_View] GTF2H3 [Vega] |
ICGC DataPortal | ENSG00000111358 |
TCGA cBioPortal | GTF2H3 |
AceView (NCBI) | GTF2H3 |
Genatlas (Paris) | GTF2H3 |
WikiGenes | 2967 |
SOURCE (Princeton) | GTF2H3 |
Genetics Home Reference (NIH) | GTF2H3 |
| Genomic and cartography |
GoldenPath hg38 (UCSC) | GTF2H3 - chr12:123633739-123662604 + 12q24.31 [Description] (hg38-Dec_2013) |
GoldenPath hg19 (UCSC) | GTF2H3 - 12q24.31 [Description] (hg19-Feb_2009) |
GoldenPath | GTF2H3 - 12q24.31 [CytoView hg19] GTF2H3 - 12q24.31 [CytoView hg38] |
ImmunoBase | ENSG00000111358 |
Mapping of homologs : NCBI | GTF2H3 [Mapview hg19] GTF2H3 [Mapview hg38] |
OMIM | 601750 |
| Gene and transcription |
Genbank (Entrez) | AK298128 AK313200 AL558542 AL600169 BC013216 |
RefSeq transcript (Entrez) | NM_001271866 NM_001271867 NM_001271868 NM_001516 |
RefSeq genomic (Entrez) | |
Consensus coding sequences : CCDS (NCBI) | GTF2H3 |
Cluster EST : Unigene | Hs.355348 [ NCBI ] |
CGAP (NCI) | Hs.355348 |
Alternative Splicing Gallery | ENSG00000111358 |
Gene Expression | GTF2H3 [ NCBI-GEO ] GTF2H3 [ EBI - ARRAY_EXPRESS ]
GTF2H3 [ SEEK ] GTF2H3 [ MEM ] |
Gene Expression Viewer (FireBrowse) | GTF2H3 [ Firebrowse - Broad ] |
SOURCE (Princeton) | Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60] |
Genevestigator | Expression in : [tissues]  [cell-lines]  [cancer]  [perturbations]   |
BioGPS (Tissue expression) | 2967 |
GTEX Portal (Tissue expression) | GTF2H3 |
Human Protein Atlas | ENSG00000111358-GTF2H3 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
UniProt/SwissProt | Q13889 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
NextProt | Q13889 [Sequence] [Exons] [Medical] [Publications] |
With graphics : InterPro | Q13889 |
Splice isoforms : SwissVar | Q13889 |
PhosPhoSitePlus | Q13889 |
Domains : Interpro (EBI) | TFIIH_Tfb4/GTF2H3 vWFA_dom_sf |
Domain families : Pfam (Sanger) | Tfb4 (PF03850) |
Domain families : Pfam (NCBI) | pfam03850 |
Conserved Domain (NCBI) | GTF2H3 |
DMDM Disease mutations | 2967 |
Blocks (Seattle) | GTF2H3 |
PDB (RSDB) | 5IVW 5IY6 5IY7 5IY8 5IY9 5O85 5OF4 |
PDB Europe | 5IVW 5IY6 5IY7 5IY8 5IY9 5O85 5OF4 |
PDB (PDBSum) | 5IVW 5IY6 5IY7 5IY8 5IY9 5O85 5OF4 |
PDB (IMB) | 5IVW 5IY6 5IY7 5IY8 5IY9 5O85 5OF4 |
Structural Biology KnowledgeBase | 5IVW 5IY6 5IY7 5IY8 5IY9 5O85 5OF4 |
SCOP (Structural Classification of Proteins) | 5IVW 5IY6 5IY7 5IY8 5IY9 5O85 5OF4 |
CATH (Classification of proteins structures) | 5IVW 5IY6 5IY7 5IY8 5IY9 5O85 5OF4 |
Superfamily | Q13889 |
Human Protein Atlas [tissue] | ENSG00000111358-GTF2H3 [tissue] |
Peptide Atlas | Q13889 |
HPRD | 07531 |
IPI | IPI00100791 IPI01011043 IPI01013414 IPI01011371 IPI01010954 IPI01010418 IPI01009488 IPI01010821 IPI01015537 IPI01009911 |
| Protein Interaction databases |
DIP (DOE-UCLA) | Q13889 |
IntAct (EBI) | Q13889 |
FunCoup | ENSG00000111358 |
BioGRID | GTF2H3 |
STRING (EMBL) | GTF2H3 |
ZODIAC | GTF2H3 |
| Ontologies - Pathways |
QuickGO | Q13889 |
Ontology : AmiGO | core TFIIH complex portion of holo TFIIH complex transcription factor TFIIH core complex nucleotide-excision repair, DNA duplex unwinding protein kinase activity protein binding nucleus nucleoplasm nucleoplasm transcription factor TFIID complex transcription factor TFIIH holo complex transcription factor TFIIH holo complex DNA repair transcription-coupled nucleotide-excision repair nucleotide-excision repair nucleotide-excision repair, preincision complex stabilization nucleotide-excision repair, preincision complex assembly nucleotide-excision repair, DNA incision, 3'-to lesion nucleotide-excision repair, DNA incision, 5'-to lesion transcription initiation from RNA polymerase I promoter transcription elongation from RNA polymerase I promoter termination of RNA polymerase I transcription transcription by RNA polymerase II transcription by RNA polymerase II transcription initiation from RNA polymerase II promoter transcription elongation from RNA polymerase II promoter 7-methylguanosine mRNA capping DNA-dependent ATPase activity DNA-dependent ATPase activity RNA polymerase II CTD heptapeptide repeat kinase activity RNA polymerase II CTD heptapeptide repeat kinase activity RNA polymerase II general transcription initiation factor activity nucleotide-excision repair, DNA incision metal ion binding protein N-terminus binding phosphorylation of RNA polymerase II C-terminal domain global genome nucleotide-excision repair transcriptional preinitiation complex |
Ontology : EGO-EBI | core TFIIH complex portion of holo TFIIH complex transcription factor TFIIH core complex nucleotide-excision repair, DNA duplex unwinding protein kinase activity protein binding nucleus nucleoplasm nucleoplasm transcription factor TFIID complex transcription factor TFIIH holo complex transcription factor TFIIH holo complex DNA repair transcription-coupled nucleotide-excision repair nucleotide-excision repair nucleotide-excision repair, preincision complex stabilization nucleotide-excision repair, preincision complex assembly nucleotide-excision repair, DNA incision, 3'-to lesion nucleotide-excision repair, DNA incision, 5'-to lesion transcription initiation from RNA polymerase I promoter transcription elongation from RNA polymerase I promoter termination of RNA polymerase I transcription transcription by RNA polymerase II transcription by RNA polymerase II transcription initiation from RNA polymerase II promoter transcription elongation from RNA polymerase II promoter 7-methylguanosine mRNA capping DNA-dependent ATPase activity DNA-dependent ATPase activity RNA polymerase II CTD heptapeptide repeat kinase activity RNA polymerase II CTD heptapeptide repeat kinase activity RNA polymerase II general transcription initiation factor activity nucleotide-excision repair, DNA incision metal ion binding protein N-terminus binding phosphorylation of RNA polymerase II C-terminal domain global genome nucleotide-excision repair transcriptional preinitiation complex |
Pathways : KEGG | Basal transcription factors Nucleotide excision repair Viral carcinogenesis |
NDEx Network | GTF2H3 |
Atlas of Cancer Signalling Network | GTF2H3 |
Wikipedia pathways | GTF2H3 |
| Orthology - Evolution |
OrthoDB | 2967 |
GeneTree (enSembl) | ENSG00000111358 |
Phylogenetic Trees/Animal Genes : TreeFam | GTF2H3 |
HOGENOM | Q13889 |
Homologs : HomoloGene | GTF2H3 |
Homology/Alignments : Family Browser (UCSC) | GTF2H3 |
| Gene fusions - Rearrangements |
Fusion : Mitelman | GTF2H3/DDX55 [12q24.31/12q24.31]   |
Fusion : Mitelman | GTF2H3/PGC [12q24.31/6p21.1]  [t(6;12)(p21;q24)] |
Fusion Portal | GTF2H3 12q24.31 PGC 6p21.1 GBM |
Fusion : Quiver | GTF2H3 |
| Polymorphisms : SNP and Copy number variants |
NCBI Variation Viewer | GTF2H3 [hg38] |
dbSNP Single Nucleotide Polymorphism (NCBI) | GTF2H3 |
dbVar | GTF2H3 |
ClinVar | GTF2H3 |
1000_Genomes | GTF2H3 |
Exome Variant Server | GTF2H3 |
ExAC (Exome Aggregation Consortium) | ENSG00000111358 |
GNOMAD Browser | ENSG00000111358 |
Varsome Browser | GTF2H3 |
Genetic variants : HAPMAP | 2967 |
Genomic Variants (DGV) | GTF2H3 [DGVbeta] |
DECIPHER | GTF2H3 [patients] [syndromes] [variants] [genes] |
CONAN: Copy Number Analysis | GTF2H3 |
| Mutations |
ICGC Data Portal | GTF2H3 |
TCGA Data Portal | GTF2H3 |
Broad Tumor Portal | GTF2H3 |
OASIS Portal | GTF2H3 [ Somatic mutations - Copy number] |
Somatic Mutations in Cancer : COSMIC | GTF2H3 [overview] [genome browser] [tissue] [distribution] |
Somatic Mutations in Cancer : COSMIC3D | GTF2H3 |
Mutations and Diseases : HGMD | GTF2H3 |
LOVD (Leiden Open Variation Database) | Whole genome datasets |
LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
BioMuta | search GTF2H3 |
DgiDB (Drug Gene Interaction Database) | GTF2H3 |
DoCM (Curated mutations) | GTF2H3 (select the gene name) |
CIViC (Clinical Interpretations of Variants in Cancer) | GTF2H3 (select a term) |
intoGen | GTF2H3 |
Cancer3D | GTF2H3(select the gene name) |
Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
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OMIM | 601750 |
Orphanet | |
DisGeNET | GTF2H3 |
Medgen | GTF2H3 |
Genetic Testing Registry | GTF2H3
|
NextProt | Q13889 [Medical] |
TSGene | 2967 |
GENETests | GTF2H3 |
Target Validation | GTF2H3 |
Huge Navigator |
GTF2H3 [HugePedia] |
snp3D : Map Gene to Disease | 2967 |
BioCentury BCIQ | GTF2H3 |
ClinGen | GTF2H3 |
| Clinical trials, drugs, therapy |
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Chemical/Protein Interactions : CTD | 2967 |
Chemical/Pharm GKB Gene | PA29043 |
Clinical trial | GTF2H3 |
| Miscellaneous |
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canSAR (ICR) | GTF2H3 (select the gene name) |
DataMed Index | GTF2H3 |
| Probes |
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| Litterature |
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PubMed | 62 Pubmed reference(s) in Entrez |
GeneRIFs | Gene References Into Functions (Entrez) |
CoreMine | GTF2H3 |
EVEX | GTF2H3 |
GoPubMed | GTF2H3 |
iHOP | GTF2H3 |