Atlas of Genetics and Cytogenetics in Oncology and Haematology

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GTF3C5 (general transcription factor IIIC subunit 5)

Identity

Alias_namesgeneral transcription factor IIIC, polypeptide 5 (63kD)
general transcription factor IIIC, polypeptide 5, 63kDa
Alias_symbol (synonym)TFiiiC2-63
TFIIIC63
TFIIICepsilon
Other alias
HGNC (Hugo) GTF3C5
LocusID (NCBI) 9328
Atlas_Id 64099
Location 9q34.13  [Link to chromosome band 9q34]
Location_base_pair Starts at 133030675 and ends at 133058503 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
IGFLR1 (19q13.12) / GTF3C5 (9q34.2)TMC4 (19q13.42) / GTF3C5 (9q34.2)WDR74 (11q12.3) / GTF3C5 (9q34.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GTF3C5   4668
Cards
Entrez_Gene (NCBI)GTF3C5  9328  general transcription factor IIIC subunit 5
AliasesTFIIIC63; TFIIICepsilon; TFiiiC2-63
GeneCards (Weizmann)GTF3C5
Ensembl hg19 (Hinxton)ENSG00000148308 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000148308 [Gene_View]  ENSG00000148308 [Sequence]  chr9:133030675-133058503 [Contig_View]  GTF3C5 [Vega]
ICGC DataPortalENSG00000148308
TCGA cBioPortalGTF3C5
AceView (NCBI)GTF3C5
Genatlas (Paris)GTF3C5
WikiGenes9328
SOURCE (Princeton)GTF3C5
Genetics Home Reference (NIH)GTF3C5
Genomic and cartography
GoldenPath hg38 (UCSC)GTF3C5  -     chr9:133030675-133058503 +  9q34.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GTF3C5  -     9q34.13   [Description]    (hg19-Feb_2009)
GoldenPathGTF3C5 - 9q34.13 [CytoView hg19]  GTF3C5 - 9q34.13 [CytoView hg38]
ImmunoBaseENSG00000148308
Mapping of homologs : NCBIGTF3C5 [Mapview hg19]  GTF3C5 [Mapview hg38]
OMIM604890   
Gene and transcription
Genbank (Entrez)AF133124 AJ420443 AK000194 AK024510 AK055092
RefSeq transcript (Entrez)NM_001122823 NM_001286709 NM_012087
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GTF3C5
Cluster EST : UnigeneHs.495417 [ NCBI ]
CGAP (NCI)Hs.495417
Alternative Splicing GalleryENSG00000148308
Gene ExpressionGTF3C5 [ NCBI-GEO ]   GTF3C5 [ EBI - ARRAY_EXPRESS ]   GTF3C5 [ SEEK ]   GTF3C5 [ MEM ]
Gene Expression Viewer (FireBrowse)GTF3C5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9328
GTEX Portal (Tissue expression)GTF3C5
Human Protein AtlasENSG00000148308-GTF3C5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y5Q8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y5Q8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y5Q8
Splice isoforms : SwissVarQ9Y5Q8
PhosPhoSitePlusQ9Y5Q8
Domains : Interpro (EBI)TF_IIIC_su-5   
Domain families : Pfam (Sanger)Tau95 (PF09734)   
Domain families : Pfam (NCBI)pfam09734   
Conserved Domain (NCBI)GTF3C5
DMDM Disease mutations9328
Blocks (Seattle)GTF3C5
SuperfamilyQ9Y5Q8
Human Protein Atlas [tissue]ENSG00000148308-GTF3C5 [tissue]
Peptide AtlasQ9Y5Q8
HPRD16077
IPIIPI00844182   IPI00411531   IPI00879210   IPI00641212   IPI00514820   IPI00748216   IPI00940853   IPI00644076   IPI00514436   IPI00642443   IPI00871523   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y5Q8
IntAct (EBI)Q9Y5Q8
FunCoupENSG00000148308
BioGRIDGTF3C5
STRING (EMBL)GTF3C5
ZODIACGTF3C5
Ontologies - Pathways
QuickGOQ9Y5Q8
Ontology : AmiGOtranscription factor TFIIIC complex  transcription factor TFIIIC complex  RNA polymerase III general transcription initiation factor activity  RNA polymerase III type 1 promoter sequence-specific DNA binding  RNA polymerase III type 2 promoter sequence-specific DNA binding  RNA polymerase III transcription regulator recruiting activity  DNA binding  protein binding  nucleoplasm  nucleoplasm  transcription by RNA polymerase III  skeletal muscle cell differentiation  5S class rRNA transcription by RNA polymerase III  tRNA transcription by RNA polymerase III  RNA polymerase III preinitiation complex assembly  
Ontology : EGO-EBItranscription factor TFIIIC complex  transcription factor TFIIIC complex  RNA polymerase III general transcription initiation factor activity  RNA polymerase III type 1 promoter sequence-specific DNA binding  RNA polymerase III type 2 promoter sequence-specific DNA binding  RNA polymerase III transcription regulator recruiting activity  DNA binding  protein binding  nucleoplasm  nucleoplasm  transcription by RNA polymerase III  skeletal muscle cell differentiation  5S class rRNA transcription by RNA polymerase III  tRNA transcription by RNA polymerase III  RNA polymerase III preinitiation complex assembly  
Pathways : BIOCARTARNA polymerase III transcription [Genes]   
NDEx NetworkGTF3C5
Atlas of Cancer Signalling NetworkGTF3C5
Wikipedia pathwaysGTF3C5
Orthology - Evolution
OrthoDB9328
GeneTree (enSembl)ENSG00000148308
Phylogenetic Trees/Animal Genes : TreeFamGTF3C5
HOGENOMQ9Y5Q8
Homologs : HomoloGeneGTF3C5
Homology/Alignments : Family Browser (UCSC)GTF3C5
Gene fusions - Rearrangements
Fusion : QuiverGTF3C5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGTF3C5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GTF3C5
dbVarGTF3C5
ClinVarGTF3C5
1000_GenomesGTF3C5 
Exome Variant ServerGTF3C5
ExAC (Exome Aggregation Consortium)ENSG00000148308
GNOMAD BrowserENSG00000148308
Varsome BrowserGTF3C5
Genetic variants : HAPMAP9328
Genomic Variants (DGV)GTF3C5 [DGVbeta]
DECIPHERGTF3C5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGTF3C5 
Mutations
ICGC Data PortalGTF3C5 
TCGA Data PortalGTF3C5 
Broad Tumor PortalGTF3C5
OASIS PortalGTF3C5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGTF3C5  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGTF3C5
Mutations and Diseases : HGMDGTF3C5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GTF3C5
DgiDB (Drug Gene Interaction Database)GTF3C5
DoCM (Curated mutations)GTF3C5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GTF3C5 (select a term)
intoGenGTF3C5
Cancer3DGTF3C5(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604890   
Orphanet
DisGeNETGTF3C5
MedgenGTF3C5
Genetic Testing Registry GTF3C5
NextProtQ9Y5Q8 [Medical]
TSGene9328
GENETestsGTF3C5
Target ValidationGTF3C5
Huge Navigator GTF3C5 [HugePedia]
snp3D : Map Gene to Disease9328
BioCentury BCIQGTF3C5
ClinGenGTF3C5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9328
Chemical/Pharm GKB GenePA29056
Clinical trialGTF3C5
Miscellaneous
canSAR (ICR)GTF3C5 (select the gene name)
DataMed IndexGTF3C5
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGTF3C5
EVEXGTF3C5
GoPubMedGTF3C5
iHOPGTF3C5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Sep 3 15:30:33 CEST 2019
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