Identity
HGNC
LOCATION
10p15.3
LOCUSID
ALIAS
CRFG,NGB,NOG1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23560
HGNC: 21535
Ensembl: ENSG00000107937
Variants:
dbSNP: 23560
ClinVar: 23560
TCGA: ENSG00000107937
COSMIC: GTPBP4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000107937 | ENST00000360059 | Q5T3R7 |
| ENSG00000107937 | ENST00000360803 | Q9BZE4 |
| ENSG00000107937 | ENST00000360803 | D2CFK9 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Ribosome biogenesis in eukaryotes | KEGG | ko03008 |
| Ribosome biogenesis in eukaryotes | KEGG | hsa03008 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37410776 | 2023 | NOG1 downregulates type I interferon production by targeting phosphorylated interferon regulatory factor 3. | 1 |
| 37410776 | 2023 | NOG1 downregulates type I interferon production by targeting phosphorylated interferon regulatory factor 3. | 1 |
| 36116159 | 2022 | GTPBP4 promotes hepatocellular carcinoma progression and metastasis via the PKM2 dependent glucose metabolism. | 17 |
| 36116159 | 2022 | GTPBP4 promotes hepatocellular carcinoma progression and metastasis via the PKM2 dependent glucose metabolism. | 17 |
| 34783233 | 2021 | LncRNA FGD5-AS1 functions as an oncogene to upregulate GTPBP4 expression by sponging miR-873-5p in hepatocellular carcinoma. | 3 |
| 34783233 | 2021 | LncRNA FGD5-AS1 functions as an oncogene to upregulate GTPBP4 expression by sponging miR-873-5p in hepatocellular carcinoma. | 3 |
| 33134380 | 2020 | Determining the Clinical Value and Critical Pathway of GTPBP4 in Lung Adenocarcinoma Using a Bioinformatics Strategy: A Study Based on Datasets from The Cancer Genome Atlas. | 7 |
| 33204302 | 2020 | An Integrating Immune-Related Signature to Improve Prognosis of Hepatocellular Carcinoma. | 9 |
| 33134380 | 2020 | Determining the Clinical Value and Critical Pathway of GTPBP4 in Lung Adenocarcinoma Using a Bioinformatics Strategy: A Study Based on Datasets from The Cancer Genome Atlas. | 7 |
| 33204302 | 2020 | An Integrating Immune-Related Signature to Improve Prognosis of Hepatocellular Carcinoma. | 9 |
| 27720713 | 2016 | Up-regulation of GTPBP4 in colorectal carcinoma is responsible for tumor metastasis. | 14 |
| 27720713 | 2016 | Up-regulation of GTPBP4 in colorectal carcinoma is responsible for tumor metastasis. | 14 |
| 17210637 | 2007 | Identification and characterization of putative tumor suppressor NGB, a GTP-binding protein that interacts with the neurofibromatosis 2 protein. | 13 |
| 17210637 | 2007 | Identification and characterization of putative tumor suppressor NGB, a GTP-binding protein that interacts with the neurofibromatosis 2 protein. | 13 |
| 16385451 | 2006 | A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. | 83 |
Citation
Dessen P
GTPBP4 (GTP binding protein 4)
Atlas Genet Cytogenet Oncol Haematol. 2007-07-01
Online version: http://atlasgeneticsoncology.org/gene/47627/gtpbp4
