Identity
HGNC
LOCATION
14q12
LOCUSID
ALIAS
C11,CCPI,CGL-1,CGL1,CSP-B,CSPB,CTLA1,CTSGL1,HLP,SECT
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3002
MIM: 123910
HGNC: 4709
Ensembl: ENSG00000100453
Variants:
dbSNP: 3002
ClinVar: 3002
TCGA: ENSG00000100453
COSMIC: GZMB
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38000677 | 2024 | Molecular and clinicopathological features of granzyme B-negative extranodal NK/T-cell lymphoma. | 0 |
| 38374566 | 2024 | Granzyme B is elevated in esophageal biopsies from children with eosinophilic esophagitis. | 0 |
| 38000677 | 2024 | Molecular and clinicopathological features of granzyme B-negative extranodal NK/T-cell lymphoma. | 0 |
| 38374566 | 2024 | Granzyme B is elevated in esophageal biopsies from children with eosinophilic esophagitis. | 0 |
| 36331826 | 2023 | Granzyme B: A novel therapeutic target for treatment of atopic dermatitis. | 2 |
| 36830757 | 2023 | Granzyme B in Autoimmune Skin Disease. | 6 |
| 36849037 | 2023 | Granzyme B Contributes to Choroidal Neovascularization and Age-Related Macular Degeneration Through Proteolysis of Thrombospondin-1. | 4 |
| 37071533 | 2023 | NK cell-derived extracellular granzyme B drives epithelial ulceration during HSV-2 genital infection. | 2 |
| 37074531 | 2023 | Human granzyme B binds Plasmodium falciparum Hsp70-x and mediates antiplasmodial activity in vitro. | 0 |
| 37196065 | 2023 | Clonally expanded, thyrotoxic effector CD8(+) T cells driven by IL-21 contribute to checkpoint inhibitor thyroiditis. | 6 |
| 37247083 | 2023 | A robust gene prognostic index composed of GZMB, IRF1, and TP63 can stratify the risk of two metastatic urothelial carcinoma cohorts based on immune checkpoint blockade therapy. | 0 |
| 37470818 | 2023 | The mRNA expression and secretion of granzyme B are up-regulated via the histamine H2 receptor in human CD4(+) T cells. | 0 |
| 38072840 | 2023 | Does the expression of granzyme B participate in inflammation, fibrosis, and fertility of hydatid cysts? | 0 |
| 36331826 | 2023 | Granzyme B: A novel therapeutic target for treatment of atopic dermatitis. | 2 |
| 36830757 | 2023 | Granzyme B in Autoimmune Skin Disease. | 6 |
Citation
Dessen P
GZMB (granzyme B)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45957/gzmb
