Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

H2BC21 (H2B clustered histone 21)

Identity

Alias_namesH2B
H2BFQ
HIST2H2BE
H2B histone family, member Q
histone 2, H2be
histone cluster 2, H2be
histone cluster 2 H2B family member e
Alias_symbol (synonym)H2B/q
H2B.1
Other aliasGL105
H2BGL105
H2BQ
HGNC (Hugo) H2BC21
LocusID (NCBI) 8349
Atlas_Id 52876
Location 1q21.2  [Link to chromosome band 1q21]
Location_base_pair Starts at 149884460 and ends at 149886682 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)H2BC21   4760
Cards
Entrez_Gene (NCBI)H2BC21  8349  H2B clustered histone 21
AliasesGL105; H2B; H2B.1; H2BFQ; 
H2BGL105; H2BQ; HIST2H2BE
GeneCards (Weizmann)H2BC21
Ensembl hg19 (Hinxton)ENSG00000184678 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000184678 [Gene_View]  ENSG00000184678 [Sequence]  chr1:149884460-149886682 [Contig_View]  H2BC21 [Vega]
ICGC DataPortalENSG00000184678
TCGA cBioPortalH2BC21
AceView (NCBI)H2BC21
Genatlas (Paris)H2BC21
WikiGenes8349
SOURCE (Princeton)H2BC21
Genetics Home Reference (NIH)H2BC21
Genomic and cartography
GoldenPath hg38 (UCSC)H2BC21  -     chr1:149884460-149886682 -  -   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)H2BC21  -     -   [Description]    (hg19-Feb_2009)
GoldenPathH2BC21 - - [CytoView hg19]  H2BC21 - - [CytoView hg38]
ImmunoBaseENSG00000184678
Mapping of homologs : NCBIH2BC21 [Mapview hg19]  H2BC21 [Mapview hg38]
OMIM601831   
Gene and transcription
Genbank (Entrez)AK093747 AK289725 BC005827 BC069193 BC096121
RefSeq transcript (Entrez)NM_003528
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)H2BC21
Cluster EST : UnigeneHs.2178 [ NCBI ]
CGAP (NCI)Hs.2178
Alternative Splicing GalleryENSG00000184678
Gene ExpressionH2BC21 [ NCBI-GEO ]   H2BC21 [ EBI - ARRAY_EXPRESS ]   H2BC21 [ SEEK ]   H2BC21 [ MEM ]
Gene Expression Viewer (FireBrowse)H2BC21 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8349
GTEX Portal (Tissue expression)H2BC21
Human Protein AtlasENSG00000184678-H2BC21 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ16778   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ16778  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ16778
Splice isoforms : SwissVarQ16778
PhosPhoSitePlusQ16778
Domaine pattern : Prosite (Expaxy)HISTONE_H2B (PS00357)   
Domains : Interpro (EBI)Histone-fold    Histone_H2A/H2B/H3    Histone_H2B   
Domain families : Pfam (Sanger)Histone (PF00125)   
Domain families : Pfam (NCBI)pfam00125   
Domain families : Smart (EMBL)H2B (SM00427)  
Conserved Domain (NCBI)H2BC21
DMDM Disease mutations8349
Blocks (Seattle)H2BC21
PDB (RSDB)4NFT   
PDB Europe4NFT   
PDB (PDBSum)4NFT   
PDB (IMB)4NFT   
Structural Biology KnowledgeBase4NFT   
SCOP (Structural Classification of Proteins)4NFT   
CATH (Classification of proteins structures)4NFT   
SuperfamilyQ16778
Human Protein Atlas [tissue]ENSG00000184678-H2BC21 [tissue]
Peptide AtlasQ16778
HPRD03494
IPIIPI00003935   
Protein Interaction databases
DIP (DOE-UCLA)Q16778
IntAct (EBI)Q16778
FunCoupENSG00000184678
BioGRIDH2BC21
STRING (EMBL)H2BC21
ZODIACH2BC21
Ontologies - Pathways
QuickGOQ16778
Ontology : AmiGOnucleosome  innate immune response in mucosa  DNA binding  DNA binding  extracellular space  nucleus  nucleus  nucleoplasm  nucleoplasm  cytosol  nucleosome assembly  nucleosome assembly  antibacterial humoral response  protein heterodimerization activity  defense response to Gram-positive bacterium  antimicrobial humoral immune response mediated by antimicrobial peptide  extracellular exosome  
Ontology : EGO-EBInucleosome  innate immune response in mucosa  DNA binding  DNA binding  extracellular space  nucleus  nucleus  nucleoplasm  nucleoplasm  cytosol  nucleosome assembly  nucleosome assembly  antibacterial humoral response  protein heterodimerization activity  defense response to Gram-positive bacterium  antimicrobial humoral immune response mediated by antimicrobial peptide  extracellular exosome  
NDEx NetworkH2BC21
Atlas of Cancer Signalling NetworkH2BC21
Wikipedia pathwaysH2BC21
Orthology - Evolution
OrthoDB8349
GeneTree (enSembl)ENSG00000184678
Phylogenetic Trees/Animal Genes : TreeFamH2BC21
HOGENOMQ16778
Homologs : HomoloGeneH2BC21
Homology/Alignments : Family Browser (UCSC)H2BC21
Gene fusions - Rearrangements
Fusion : QuiverH2BC21
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerH2BC21 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)H2BC21
dbVarH2BC21
ClinVarH2BC21
1000_GenomesH2BC21 
Exome Variant ServerH2BC21
ExAC (Exome Aggregation Consortium)ENSG00000184678
GNOMAD BrowserENSG00000184678
Varsome BrowserH2BC21
Genetic variants : HAPMAP8349
Genomic Variants (DGV)H2BC21 [DGVbeta]
DECIPHERH2BC21 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisH2BC21 
Mutations
ICGC Data PortalH2BC21 
TCGA Data PortalH2BC21 
Broad Tumor PortalH2BC21
OASIS PortalH2BC21 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDH2BC21
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch H2BC21
DgiDB (Drug Gene Interaction Database)H2BC21
DoCM (Curated mutations)H2BC21 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)H2BC21 (select a term)
intoGenH2BC21
Cancer3DH2BC21(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601831   
Orphanet
DisGeNETH2BC21
MedgenH2BC21
Genetic Testing Registry H2BC21
NextProtQ16778 [Medical]
TSGene8349
GENETestsH2BC21
Target ValidationH2BC21
Huge Navigator H2BC21 [HugePedia]
snp3D : Map Gene to Disease8349
BioCentury BCIQH2BC21
ClinGenH2BC21
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8349
Chemical/Pharm GKB GenePA29135
Clinical trialH2BC21
Miscellaneous
canSAR (ICR)H2BC21 (select the gene name)
DataMed IndexH2BC21
Probes
Litterature
PubMed180 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineH2BC21
EVEXH2BC21
GoPubMedH2BC21
iHOPH2BC21
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 13 17:46:06 CET 2019

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.