HABP2 (hyaluronan binding protein 2)

2015-08-01  

Identity

HGNC
HABP2
LOCATION
10q25.3
LOCUSID
3026
ALIAS
FSAP,HABP,HGFAL,NMTC5,PHBP

Other Information

Locus ID:

NCBI: 3026
MIM: 603924
HGNC: 4798
Ensembl: ENSG00000148702

Variants:

dbSNP: 3026
ClinVar: 3026
TCGA: ENSG00000148702
COSMIC: HABP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000148702ENST00000351270Q14520
ENSG00000148702ENST00000542051Q14520

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.69
262225602015Germline HABP2 Mutation Causing Familial Nonmedullary Thyroid Cancer.30
156547662005Extracellular RNA is a natural cofactor for the (auto-)activation of Factor VII-activating protease (FSAP).21
200427072010Hyaluronic Acid binding protein 2 is a novel regulator of vascular integrity.21
171459542006The G534E polymorphism of the gene encoding the factor VII-activating protease is associated with cardiovascular risk due to increased neointima formation.17
223083062012Factor VII-activating protease is activated in multiple trauma patients and generates anaphylatoxin C5a.16
154860682005Marburg I polymorphism of factor VII-activating protease is associated with idiopathic venous thromboembolism.15
154860682005Marburg I polymorphism of factor VII-activating protease is associated with idiopathic venous thromboembolism.15
216008852011Extracellular histone induces plasma hyaluronan-binding protein (factor VII activating protease) activation in vivo.15

Citation

Dessen P

HABP2 (hyaluronan binding protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2015-08-01

Online version: http://atlasgeneticsoncology.org/gene/55332/habp2