HAO2 (hydroxyacid oxidase 2)

2014-08-01  

Identity

HGNC
LOCATION
1p12
LOCUSID
ALIAS
GIG16,HAOX2
FUSION GENES

Other Information

Locus ID:

NCBI: 51179
MIM: 605176
HGNC: 4810
Ensembl: ENSG00000116882

Variants:

dbSNP: 51179
ClinVar: 51179
TCGA: ENSG00000116882
COSMIC: HAO2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000116882ENST00000325945Q9NYQ3
ENSG00000116882ENST00000361035Q9NYQ3
ENSG00000116882ENST00000457318Q5QP02
ENSG00000116882ENST00000622548Q9NYQ3

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Glyoxylate and dicarboxylate metabolismKEGGko00630
Glyoxylate and dicarboxylate metabolismKEGGhsa00630
PeroxisomeKEGGko04146
PeroxisomeKEGGhsa04146
Metabolic pathwaysKEGGhsa01100
Carbon metabolismKEGGhsa01200
Carbon metabolismKEGGko01200
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Peroxisomal lipid metabolismREACTOMER-HSA-390918

References

Pubmed IDYearTitleCitations
196921682010Genetic susceptibility to distinct bladder cancer subphenotypes.25
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
266586812016The metabolic gene HAO2 is downregulated in hepatocellular carcinoma and predicts metastasis and poor survival.11
311276262019HAO2 inhibits malignancy of clear cell renal cell carcinoma by promoting lipid catabolic process.2

Citation

Dessen P

HAO2 (hydroxyacid oxidase 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54351/hao2