HCP5 (HLA complex P5)

2014-05-01 Affiliation

Identity

HGNC

HCP5

LOCATION

6p21.33

LOCUSID

10866

ALIAS

6S2650E,D6S2650E,P5-1

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 10866
MIM: 604676
HGNC: 21659
Ensembl: ENSG00000206337

Variants:

dbSNP: 10866
ClinVar: 10866
TCGA: ENSG00000206337
COSMIC: HCP5

RNA/Proteins

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

PharmGKB

Entity ID	Name	Type	Evidence	Association	PD	PMIDs
PA443622	Carcinoma, Non-Small-Cell Lung	Disease	ClinicalAnnotation	associated	PD	31616045
PA445846	Thrombocytopenia	Disease	ClinicalAnnotation	associated	PD	31616045
PA448803	carboplatin	Chemical	ClinicalAnnotation	associated	PD	31616045
PA449748	gemcitabine	Chemical	ClinicalAnnotation	associated	PD	31616045
PA450616	nevirapine	Chemical	Literature, MultilinkAnnotation	associated		24322967

References

Pubmed ID	Year	Title	Citations
19115949	2009	Genomewide association study of an AIDS-nonprogression cohort emphasizes the role played by HLA genes (ANRS Genomewide Association Study 02).	119
19851445	2009	High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.	51
19050382	2009	Association of HLA-C and HCP5 gene regions with the clinical course of HIV-1 infection.	44
18982067	2008	HIV-1 disease-influencing effects associated with ZNRD1, HCP5 and HLA-C alleles are attributable mainly to either HLA-A10 or HLA-B*57 alleles.	40
18982067	2008	HIV-1 disease-influencing effects associated with ZNRD1, HCP5 and HLA-C alleles are attributable mainly to either HLA-A10 or HLA-B*57 alleles.	40
27434586	2016	Role of HCP5-miR-139-RUNX1 Feedback Loop in Regulating Malignant Behavior of Glioma Cells.	34
18684101	2008	The HCP5 single-nucleotide polymorphism: a simple screening tool for prediction of hypersensitivity reaction to abacavir.	24
18684101	2008	The HCP5 single-nucleotide polymorphism: a simple screening tool for prediction of hypersensitivity reaction to abacavir.	24
23665287	2013	Comparative genetic analyses point to HCP5 as susceptibility locus for HCV-associated hepatocellular carcinoma.	23
31131047	2019	HCP5 is a SMAD3-responsive long non-coding RNA that promotes lung adenocarcinoma metastasis via miR-203/SNAI axis.	21

Citation

Dessen P

HCP5 (HLA complex P5)

Atlas Genet Cytogenet Oncol Haematol. 2014-05-01

Online version: http://atlasgeneticsoncology.org/gene/53883/hcp5