HDGFL2 (HDGF like 2)

2017-04-01  

Identity

HGNC
HDGFL2
LOCATION
19p13.3
LOCUSID
84717
ALIAS
HDGF-2,HDGF2,HDGFRP2,HRP-2,HRP2

Other Information

Locus ID:

NCBI: 84717
MIM: 617884
HGNC: 14680
Ensembl: ENSG00000167674

Variants:

dbSNP: 84717
ClinVar: 84717
TCGA: ENSG00000167674
COSMIC: HDGFL2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167674ENST00000587016K7ERA4
ENSG00000167674ENST00000589486K7EJP7
ENSG00000167674ENST00000592417K7EPS6
ENSG00000167674ENST00000592691K7EQ06
ENSG00000167674ENST00000601353M0R0J3
ENSG00000167674ENST00000614903A0A087WZ99
ENSG00000167674ENST00000615225A0A087WT54
ENSG00000167674ENST00000616600Q7Z4V5
ENSG00000167674ENST00000619255A0A087WX58
ENSG00000167674ENST00000621835Q7Z4V5

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
163379832006Biochemical and genetic analyses of integrase-interacting proteins lens epithelium-derived growth factor (LEDGF)/p75 and hepatoma-derived growth factor related protein 2 (HRP2) in preintegration complex function and HIV-1 replication.57
230466032012HRP-2 determines HIV-1 integration site selection in LEDGF/p75 depleted cells.29
267213872016Hepatoma-derived growth factor-related protein 2 promotes DNA repair by homologous recombination.8
316167952019LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription in differentiated cells.3
256897192015HDGF-related protein-2 (HRP-2) acts as an oncogene to promote cell growth in hepatocellular carcinoma.1

Citation

Dessen P

HDGFL2 (HDGF like 2)

Atlas Genet Cytogenet Oncol Haematol. 2017-04-01

Online version: http://atlasgeneticsoncology.org/gene/56870/hdgfl2