HDGFL3 (HDGF like 3)

2017-04-01  

Identity

HGNC
HDGFL3
LOCATION
15q25.2
LOCUSID
50810
ALIAS
CGI-142,HDGF-2,HDGF2,HDGFRP3,HRP-3

Other Information

Locus ID:

NCBI: 50810
MIM: 616643
HGNC: 24937
Ensembl: ENSG00000166503

Variants:

dbSNP: 50810
ClinVar: 50810
TCGA: ENSG00000166503
COSMIC: HDGFL3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166503ENST00000299633Q9Y3E1
ENSG00000166503ENST00000299633A0A024R216
ENSG00000166503ENST00000563404H3BPQ6
ENSG00000166503ENST00000563790H3BPQ6
ENSG00000166503ENST00000568294H3BPM9

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
153714382004Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase.128
192375402009Hepatoma-derived growth factor-related protein-3 interacts with microtubules and promotes neurite outgrowth in mouse cortical neurons.5
240126732013Depletion of hepatoma-derived growth factor-related protein-3 induces apoptotic sensitization of radioresistant A549 cells via reactive oxygen species-dependent p53 activation.2
268237542015HRP-3 protects the hepatoma cells from glucose deprivation-induced apoptosis.2
311626072019The HRP3 PWWP domain recognizes the minor groove of double-stranded DNA and recruits HRP3 to chromatin.2

Citation

Dessen P

HDGFL3 (HDGF like 3)

Atlas Genet Cytogenet Oncol Haematol. 2017-04-01

Online version: http://atlasgeneticsoncology.org/gene/56766/hdgfl3