HECTD4 (HECT domain E3 ubiquitin protein ligase 4)

2015-10-01  

Identity

HGNC
LOCATION
12q24.13
LOCUSID
ALIAS
C12ord51,C12orf51,HEEL,POTAGE
FUSION GENES

Other Information

Locus ID:

NCBI: 283450
HGNC: 26611
Ensembl: ENSG00000173064

Variants:

dbSNP: 283450
ClinVar: 283450
TCGA: ENSG00000173064
COSMIC: HECTD4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000173064ENST00000377560J3KPF0
ENSG00000173064ENST00000548588V9GYT9
ENSG00000173064ENST00000550722F8VWT9
ENSG00000173064ENST00000550724F8VU57
ENSG00000173064ENST00000651701A0A494C150

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
235754362013New susceptibility loci in MYL2, C12orf51 and OAS1 associated with 1-h plasma glucose as predisposing risk factors for type 2 diabetes in the Korean population.14
256613492015Genetic variation in C12orf51 is associated with prognosis of intestinal-type gastric cancer in a Chinese population.0
266750162015A Genome-Wide Association Study Uncovers a Genetic Locus Associated with Thoracic-to-Hip Ratio in Koreans.0
282126322017Exome-wide association study identifies genetic polymorphisms of C12orf51, MYL2, and ALDH2 associated with blood lead levels in the general Korean population.0

Citation

Dessen P

HECTD4 (HECT domain E3 ubiquitin protein ligase 4)

Atlas Genet Cytogenet Oncol Haematol. 2015-10-01

Online version: http://atlasgeneticsoncology.org/gene/55498/hectd4