Identity
HGNC
LOCATION
17q21.31
LOCUSID
ALIAS
CLP1,EDG1,HIS1,MAQ1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10614
MIM: 607328
HGNC: 24953
Ensembl: ENSG00000186834
Variants:
dbSNP: 10614
ClinVar: 10614
TCGA: ENSG00000186834
COSMIC: HEXIM1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000186834 | ENST00000332499 | O94992 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37738561 | 2023 | HEXIM1 is an essential transcription regulator during human erythropoiesis. | 1 |
| 37738561 | 2023 | HEXIM1 is an essential transcription regulator during human erythropoiesis. | 1 |
| 34864989 | 2022 | Downregulation of Dihydrotestosterone and Estradiol Levels by HEXIM1. | 1 |
| 34864989 | 2022 | Downregulation of Dihydrotestosterone and Estradiol Levels by HEXIM1. | 1 |
| 34465029 | 2021 | UHRF1 Suppresses HIV-1 Transcription and Promotes HIV-1 Latency by Competing with p-TEFb for Ubiquitination-Proteasomal Degradation of Tat. | 7 |
| 34465029 | 2021 | UHRF1 Suppresses HIV-1 Transcription and Promotes HIV-1 Latency by Competing with p-TEFb for Ubiquitination-Proteasomal Degradation of Tat. | 7 |
| 31732748 | 2020 | Structural transitions in the RNA 7SK 5' hairpin and their effect on HEXIM binding. | 13 |
| 32520633 | 2020 | HEXIM1 controls P-TEFb processing and regulates drug sensitivity in triple-negative breast cancer. | 6 |
| 31732748 | 2020 | Structural transitions in the RNA 7SK 5' hairpin and their effect on HEXIM binding. | 13 |
| 32520633 | 2020 | HEXIM1 controls P-TEFb processing and regulates drug sensitivity in triple-negative breast cancer. | 6 |
| 31590891 | 2019 | HEXIM1 Diffusion in the Nucleus Is Regulated by Its Interactions with Both 7SK and P-TEFb. | 2 |
| 31776402 | 2019 | Phosphorylation of the histone demethylase KDM5B and regulation of the phenotype of triple negative breast cancer. | 11 |
| 31805991 | 2019 | Inhibition of the histone demethylase, KDM5B, directly induces re-expression of tumor suppressor protein HEXIM1 in cancer cells. | 14 |
| 31590891 | 2019 | HEXIM1 Diffusion in the Nucleus Is Regulated by Its Interactions with Both 7SK and P-TEFb. | 2 |
| 31776402 | 2019 | Phosphorylation of the histone demethylase KDM5B and regulation of the phenotype of triple negative breast cancer. | 11 |
Citation
Dessen P
HEXIM1 (HEXIM P-TEFb complex subunit 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/43034/hexim1
