Identity
HGNC
LOCATION
10q23.33
LOCUSID
ALIAS
HEX,HMPH,HOX11L-PEN,PRH,PRHX
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3087
MIM: 604420
HGNC: 4901
Ensembl: ENSG00000152804
Variants:
dbSNP: 3087
ClinVar: 3087
TCGA: ENSG00000152804
COSMIC: HHEX
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000152804 | ENST00000282728 | Q03014 |
| ENSG00000152804 | ENST00000472590 | F8VU08 |
| ENSG00000152804 | ENST00000492654 | F8VU08 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37103601 | 2023 | Association of HHEX and SLC30A8 Gene Polymorphisms with Gestational Diabetes Mellitus Susceptibility: A Meta-analysis. | 4 |
| 37248264 | 2023 | Elucidation of HHEX in pancreatic endoderm differentiation using a human iPSC differentiation model. | 2 |
| 37302518 | 2023 | HHEX suppresses advanced thyroid cancer by interacting with TLE3. | 3 |
| 37103601 | 2023 | Association of HHEX and SLC30A8 Gene Polymorphisms with Gestational Diabetes Mellitus Susceptibility: A Meta-analysis. | 4 |
| 37248264 | 2023 | Elucidation of HHEX in pancreatic endoderm differentiation using a human iPSC differentiation model. | 2 |
| 37302518 | 2023 | HHEX suppresses advanced thyroid cancer by interacting with TLE3. | 3 |
| 35887298 | 2022 | Unraveling the Influence of HHEX Risk Polymorphism rs7923837 on Multiple Sclerosis Pathogenesis. | 1 |
| 36008411 | 2022 | CK2-induced cooperation of HHEX with the YAP-TEAD4 complex promotes colorectal tumorigenesis. | 9 |
| 35887298 | 2022 | Unraveling the Influence of HHEX Risk Polymorphism rs7923837 on Multiple Sclerosis Pathogenesis. | 1 |
| 36008411 | 2022 | CK2-induced cooperation of HHEX with the YAP-TEAD4 complex promotes colorectal tumorigenesis. | 9 |
| 34321041 | 2021 | Hhex inhibits cell migration via regulating RHOA/CDC42-CFL1 axis in human lung cancer cells. | 6 |
| 34623901 | 2021 | Integrated single-cell transcriptomics and epigenomics reveals strong germinal center-associated etiology of autoimmune risk loci. | 10 |
| 34321041 | 2021 | Hhex inhibits cell migration via regulating RHOA/CDC42-CFL1 axis in human lung cancer cells. | 6 |
| 34623901 | 2021 | Integrated single-cell transcriptomics and epigenomics reveals strong germinal center-associated etiology of autoimmune risk loci. | 10 |
| 31843982 | 2020 | A Runaway PRH/HHEX-Notch3-Positive Feedback Loop Drives Cholangiocarcinoma and Determines Response to CDK4/6 Inhibition. | 12 |
Citation
Dessen P
HHEX (hematopoietically expressed homeobox)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46061/hhex
