HINFP (histone H4 transcription factor)

2007-02-01  

Identity

HGNC
LOCATION
11q23.3
LOCUSID
ALIAS
HiNF-P,MIZF,ZNF743

Other Information

Locus ID:

NCBI: 25988
MIM: 607099
HGNC: 17850
Ensembl: ENSG00000172273

Variants:

dbSNP: 25988
ClinVar: 25988
TCGA: ENSG00000172273
COSMIC: HINFP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000172273ENST00000350777Q9BQA5
ENSG00000172273ENST00000350777A0A024R3F5
ENSG00000172273ENST00000527410Q9BQA5
ENSG00000172273ENST00000529988E9PL67
ENSG00000172273ENST00000530678E9PJA3

Expression (GTEx)

0
5
10
15
20
25
30

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
159880252005HiNF-P directly links the cyclin E/CDK2/p220NPAT pathway to histone H4 gene regulation at the G1/S phase cell cycle transition.49
145859712003Identification of HiNF-P, a key activator of cell cycle-controlled histone H4 genes at the onset of S phase.27
167860002006CpG island promoter methylation and silencing of 14-3-3sigma gene expression in LNCaP and Tramp-C1 prostate cancer cell lines is associated with methyl-CpG-binding protein MBD2.21
171761142006The histone gene transcription factor HiNF-P stabilizes its cell cycle regulatory co-activator p220NPAT.13
179749762007The HiNF-P/p220NPAT cell cycle signaling pathway controls nonhistone target genes.11
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
191701052009CDK inhibitors selectively diminish cell cycle controlled activation of the histone H4 gene promoter by p220NPAT and HiNF-P.9
170494872006RET finger protein enhances MBD2- and MBD4-dependent transcriptional repression.7
171634572007HiNF-P is a bifunctional regulator of cell cycle controlled histone H4 gene transcription.7

Citation

Dessen P

HINFP (histone H4 transcription factor)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45595/hinfp