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HLA-B (major histocompatibility complex, class I, B)

Identity

Alias (NCBI)AS
B-4901
HLAB
HGNC (Hugo) HLA-B
HGNC Previous nameAS
HGNC Previous nameankylosing spondylitis
LocusID (NCBI) 3106
Atlas_Id 46594
Location 6p21.33  [Link to chromosome band 6p21]
Location_base_pair Starts at 31353875 and ends at 31357179 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ACTR1B (2q11.2) / HLA-B (6p21.33)ANKLE2 (12q24.33) / HLA-B (6p21.33)HLA-A (6p22.1) / HLA-B (6p21.33)
HLA-B (6p21.33) / APOL3 (22q12.3)HLA-B (6p21.33) / CAMK4 (5q22.1)HLA-B (6p21.33) / CCT7 (2p13.2)
HLA-B (6p21.33) / CYTH2 (19q13.33)HLA-B (6p21.33) / FECH (18q21.31)HLA-B (6p21.33) / FKBP8 (19p13.11)
HLA-B (6p21.33) / HLA-B (6p21.33)HLA-B (6p21.33) / IGKC (2p11.2)HLA-B (6p21.33) / OGT (Xq13.1)
HLA-B (6p21.33) / ORAI2 (7q22.1)HLA-B (6p21.33) / PSMB3 (17q12)HLA-B (6p21.33) / RNASEH2B (13q14.3)
HLA-B (6p21.33) / RPL3 (22q13.1)HLA-B (6p21.33) / SBK1 (16p11.2)HLA-B (6p21.33) / SEPT2 (2q37.3)
HLA-B (6p21.33) / TACC1 (8p11.22)HLA-C (6p21.33) / HLA-B (6p21.33)HLA-E (6p21.33) / HLA-B (6p21.33)
HLA-G (6p22.1) / HLA-B (6p21.33)HLA-H (6p22.1) / HLA-B (6p21.33)HLA-J (6p22.1) / HLA-B (6p21.33)
HLA-L (6p22.1) / HLA-B (6p21.33)KCNQ1 (11p15.5) / HLA-B (6p21.33)MUC16 (19p13.2) / HLA-B (6p21.33)
NACA (12q13.3) / HLA-B (6p21.33)TRPC6 (11q22.1) / HLA-B (6p21.33)HLA-B 6p21.33 / RNASEH2B 13q14.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  HLA-E/HLA-B (6p21)
t(6;13)(p21;q14) HLA-B/RNASEH2B


External links

Nomenclature
HGNC (Hugo)HLA-B   4932
Cards
Entrez_Gene (NCBI)HLA-B    major histocompatibility complex, class I, B
AliasesAS; B-4901; HLAB
GeneCards (Weizmann)HLA-B
Ensembl hg19 (Hinxton)ENSG00000234745 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000234745 [Gene_View]  ENSG00000234745 [Sequence]  chr6:31353875-31357179 [Contig_View]  HLA-B [Vega]
ICGC DataPortalENSG00000234745
TCGA cBioPortalHLA-B
AceView (NCBI)HLA-B
Genatlas (Paris)HLA-B
SOURCE (Princeton)HLA-B
Genetics Home Reference (NIH)HLA-B
Genomic and cartography
GoldenPath hg38 (UCSC)HLA-B  -     chr6:31353875-31357179 -  6p21.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HLA-B  -     6p21.33   [Description]    (hg19-Feb_2009)
GoldenPathHLA-B - 6p21.33 [CytoView hg19]  HLA-B - 6p21.33 [CytoView hg38]
ImmunoBaseENSG00000234745
genome Data Viewer NCBIHLA-B [Mapview hg19]  
OMIM106300   142830   608579   
Gene and transcription
Genbank (Entrez)AB008102 AF004370 AF006634 AF016641 AF022783
RefSeq transcript (Entrez)NM_005514
RefSeq genomic (Entrez)NC_000006 NG_023187 NT_113891 NT_167246 NT_167247 NT_167248 NT_167249
Consensus coding sequences : CCDS (NCBI)HLA-B
Alternative Splicing GalleryENSG00000234745
Gene ExpressionHLA-B [ NCBI-GEO ]   HLA-B [ EBI - ARRAY_EXPRESS ]   HLA-B [ SEEK ]   HLA-B [ MEM ]
Gene Expression Viewer (FireBrowse)HLA-B [ Firebrowse - Broad ]
GenevisibleExpression of HLA-B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3106
GTEX Portal (Tissue expression)HLA-B
Human Protein AtlasENSG00000234745-HLA-B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)HLA-B
Blocks (Seattle)HLA-B
Human Protein Atlas [tissue]ENSG00000234745-HLA-B [tissue]
HPRD00828
Protein Interaction databases
BioGRIDHLA-B
STRING (EMBL)HLA-B
ZODIACHLA-B
Ontologies - Pathways
Litterature
PubMed499 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXHLA-B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jan 1 18:18:47 CET 2021

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