Identity
HGNC
LOCATION
6p21.32
LOCUSID
ALIAS
DOB,HLA_DOB
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3112
MIM: 600629
HGNC: 4937
Ensembl: ENSG00000241106
Variants:
dbSNP: 3112
ClinVar: 3112
TCGA: ENSG00000241106
COSMIC: HLA-DOB
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36389712 | 2022 | MUC22, HLA-A, and HLA-DOB variants and COVID-19 in resilient super-agers from Brazil. | 7 |
| 36389712 | 2022 | MUC22, HLA-A, and HLA-DOB variants and COVID-19 in resilient super-agers from Brazil. | 7 |
| 28813660 | 2017 | Neutralizing Antibody Responses to Viral Infections Are Linked to the Non-classical MHC Class II Gene H2-Ob. | 33 |
| 28813660 | 2017 | Neutralizing Antibody Responses to Viral Infections Are Linked to the Non-classical MHC Class II Gene H2-Ob. | 33 |
| 25874709 | 2015 | Association of polymorphisms in HLA antigen presentation-related genes with the outcomes of HCV infection. | 8 |
| 25874709 | 2015 | Association of polymorphisms in HLA antigen presentation-related genes with the outcomes of HCV infection. | 8 |
| 23222639 | 2013 | HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism. | 71 |
| 23400868 | 2013 | Ubiquitination of HLA-DO by MARCH family E3 ligases. | 14 |
| 23222639 | 2013 | HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism. | 71 |
| 23400868 | 2013 | Ubiquitination of HLA-DO by MARCH family E3 ligases. | 14 |
| 20237496 | 2010 | New genetic associations detected in a host response study to hepatitis B vaccine. | 37 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20237496 | 2010 | New genetic associations detected in a host response study to hepatitis B vaccine. | 37 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 19851445 | 2009 | High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. | 58 |
Citation
Dessen P
HLA-DOB (major histocompatibility complex, class II, DO beta)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46359/hla-dob
