| Nomenclature |
|---|
| HGNC (Hugo) | HMX1 5017 |
| Cards |
|---|
| Entrez_Gene (NCBI) | HMX1 3166 H6 family homeobox 1 |
| Aliases | H6; NKX5-3 |
| GeneCards (Weizmann) | HMX1 |
| Ensembl hg19 (Hinxton) | ENSG00000215612 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000215612 [Gene_View] ENSG00000215612 [Sequence] chr4:8846076-8871817 [Contig_View] HMX1 [Vega] |
| ICGC DataPortal | ENSG00000215612 |
| TCGA cBioPortal | HMX1 |
| AceView (NCBI) | HMX1 |
| Genatlas (Paris) | HMX1 |
| WikiGenes | 3166 |
| SOURCE (Princeton) | HMX1 |
| Genetics Home Reference (NIH) | HMX1 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | HMX1 - chr4:8846076-8871817 - 4p16.1 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | HMX1 - 4p16.1 [Description] (hg19-Feb_2009) |
| GoldenPath | HMX1 - 4p16.1 [CytoView hg19] HMX1 - 4p16.1 [CytoView hg38] |
| ImmunoBase | ENSG00000215612 |
| Mapping of homologs : NCBI | HMX1 [Mapview hg19] HMX1 [Mapview hg38] |
| OMIM | 142992 612109 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AB593128 BM701514 CK299519 M99587 |
| RefSeq transcript (Entrez) | NM_001306142 NM_018942 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | HMX1 |
| Cluster EST : Unigene | Hs.104134 [ NCBI ] |
| CGAP (NCI) | Hs.104134 |
| Alternative Splicing Gallery | ENSG00000215612 |
| Gene Expression | HMX1 [ NCBI-GEO ] HMX1 [ EBI - ARRAY_EXPRESS ]
HMX1 [ SEEK ] HMX1 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | HMX1 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 3166 |
| GTEX Portal (Tissue expression) | HMX1 |
| Human Protein Atlas | ENSG00000215612-HMX1 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q9NP08 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | Q9NP08 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | Q9NP08 |
| Splice isoforms : SwissVar | Q9NP08 |
| PhosPhoSitePlus | Q9NP08 |
| Domaine pattern : Prosite (Expaxy) | HOMEOBOX_1 (PS00027) HOMEOBOX_2 (PS50071) |
| Domains : Interpro (EBI) | Homeobox-like_sf Homeobox_CS Homeobox_dom Homeobox_metazoa |
| Domain families : Pfam (Sanger) | Homeobox (PF00046) |
| Domain families : Pfam (NCBI) | pfam00046 |
| Domain families : Smart (EMBL) | HOX (SM00389) |
| Conserved Domain (NCBI) | HMX1 |
| DMDM Disease mutations | 3166 |
| Blocks (Seattle) | HMX1 |
| Superfamily | Q9NP08 |
| Human Protein Atlas [tissue] | ENSG00000215612-HMX1 [tissue] |
| Peptide Atlas | Q9NP08 |
| HPRD | 00873 |
| IPI | IPI00004379 IPI01017998 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q9NP08 |
| IntAct (EBI) | Q9NP08 |
| FunCoup | ENSG00000215612 |
| BioGRID | HMX1 |
| STRING (EMBL) | HMX1 |
| ZODIAC | HMX1 |
| Ontologies - Pathways |
|---|
| QuickGO | Q9NP08 |
| Ontology : AmiGO | negative regulation of transcription by RNA polymerase II RNA polymerase II regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding nucleus multicellular organism development negative regulation of transcription, DNA-templated |
| Ontology : EGO-EBI | negative regulation of transcription by RNA polymerase II RNA polymerase II regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding nucleus multicellular organism development negative regulation of transcription, DNA-templated |
| NDEx Network | HMX1 |
| Atlas of Cancer Signalling Network | HMX1 |
| Wikipedia pathways | HMX1 |
| Orthology - Evolution |
|---|
| OrthoDB | 3166 |
| GeneTree (enSembl) | ENSG00000215612 |
| Phylogenetic Trees/Animal Genes : TreeFam | HMX1 |
| HOGENOM | Q9NP08 |
| Homologs : HomoloGene | HMX1 |
| Homology/Alignments : Family Browser (UCSC) | HMX1 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | HMX1 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | HMX1 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | HMX1 |
| dbVar | HMX1 |
| ClinVar | HMX1 |
| 1000_Genomes | HMX1 |
| Exome Variant Server | HMX1 |
| ExAC (Exome Aggregation Consortium) | ENSG00000215612 |
| GNOMAD Browser | ENSG00000215612 |
| Varsome Browser | HMX1 |
| Genetic variants : HAPMAP | 3166 |
| Genomic Variants (DGV) | HMX1 [DGVbeta] |
| DECIPHER | HMX1 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | HMX1 |
| Mutations |
|---|
| ICGC Data Portal | HMX1 |
| TCGA Data Portal | HMX1 |
| Broad Tumor Portal | HMX1 |
| OASIS Portal | HMX1 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | HMX1 [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | HMX1 |
| Mutations and Diseases : HGMD | HMX1 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search HMX1 |
| DgiDB (Drug Gene Interaction Database) | HMX1 |
| DoCM (Curated mutations) | HMX1 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | HMX1 (select a term) |
| intoGen | HMX1 |
| Cancer3D | HMX1(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 142992 612109 |
| Orphanet | 17163 |
| DisGeNET | HMX1 |
| Medgen | HMX1 |
| Genetic Testing Registry | HMX1
|
| NextProt | Q9NP08 [Medical] |
| TSGene | 3166 |
| GENETests | HMX1 |
| Target Validation | HMX1 |
| Huge Navigator |
HMX1 [HugePedia] |
| snp3D : Map Gene to Disease | 3166 |
| BioCentury BCIQ | HMX1 |
| ClinGen | HMX1 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 3166 |
| Chemical/Pharm GKB Gene | PA29344 |
| Clinical trial | HMX1 |
| Miscellaneous |
|---|
| canSAR (ICR) | HMX1 (select the gene name) |
| DataMed Index | HMX1 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 11 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | HMX1 |
| EVEX | HMX1 |
| GoPubMed | HMX1 |
| iHOP | HMX1 |
